Episkin products

T-Skin is an in vitro reconstructed skin which consists of a dermal equivalent with human fibroblasts overlaid by a stratified, well differentiated epidermis derived from normal human keratinocytes cultured on an inert polycarbonate filter. This model exists at different stages of maturity.

The SkinEthic RHPE model is composed of normal human keratinocytes cultivated in the presence of melanocytes of phototype II (Light), IV (Tanned) or VI (Brown), localized in the basal layer. The different tanning degrees of these constructs correspond macroscopically to 3 different phototypes of human ski

The SkinEthic RHE-LC model is a standard epidermal model in which Langerhans cells progenitors have been integrated. During the tissue reconstruction, these immature cells have differentiated into antigen-presenting Langerhans cells expressing the specific marker CD207 (langerin). They are mostly located and evenly spread within the supra-basal epidermal layer.  The SkinEthic™ RHE-LC model is therefore expected to be a useful tool for skin immune response studies.

SkinEthicTM RHEACF is an in vitro reconstructed human epidermis from normal human keratinocytes cultured on an inert polycarbonate filter at the air-liquid interface, in a chemically defined medium. Improved production so every single process is guaranteed devoid of any animal constituents and tissue production now guaranteed devoid of any animal components with traceability of all ingredients. This model exists at different stages of maturity. This model is histologically similar to in vivo human epidermis.

SkinEthic RHE is an in vitro reconstructed human epidermis from normal human keratinocytes cultured on an inert polycarbonate filter at the air-liquid interface, in a chemically defined medium. This model exists at different stages of maturity. This model is histologically similar to in vivo human epidermis.