Episkin
SkinEthic - Model RHE ACF - Reconstructed Human Epidermis Animal Component Free
FromEpiskin
SkinEthicTM RHEACF is an in vitro reconstructed human epidermis from normal human keratinocytes cultured on an inert polycarbonate filter at the air-liquid interface, in a chemically defined medium. Improved production so every single process is guaranteed devoid of any animal constituents and tissue production now guaranteed devoid of any animal components with traceability of all ingredients. This model exists at different stages of maturity. This model is histologically similar to in vivo human epidermis.
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Differentiation markers:
- Filaggrin (See picture)
- Involucrin
- Loricrin (See picture)
- Transglutaminase
- Keratin 10 (See picture)
- Keratin 5
- CD44 (See picture)
- Presence of different epidermal classes of lipids comprising ceramides
Dermal-Epidermal junction markers
- Type IV collagen
- Laminin V
- Alpha6Beta4-integrin
- BP antigen
Proliferation markers
- Ki67 (See picture)
- 0.5 cm² (See picture)
- 4 cm² (See picture)
- HTS 24-well plate 0.33 cm² (See picture)
- HTS 96-well plate 0.11 cm² (See picture)