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Medchemexpress Cell Based Therapy Equipment & Supplies

30 equipment items found

MedChemExpress - Model Cibinetide - 1208243-50-8

MedChemExpress - Model Cibinetide - 1208243-50-8

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Cibinetide (ARA290) is an EPO-derivative, acting as a specific agonist of erythropoietin/CD131 heteroreceptor, and used for neurological disease ...
CONTACT SUPPLIER

MedChemExpress - Model Oxyfedrine hydrochloride - 16777-42-7

MedChemExpress - Model Oxyfedrine hydrochloride - 16777-42-7

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Oxyfedrine hydrochloride, a vasodilator, is an orally active β-adrenoreceptor agonist. Oxyfedrine decreases the tonicity of coronary vessels. Oxyfedrine hydrochloride can be used in the research of cardiovascular ...
CONTACT SUPPLIER

MedChemExpress - Model Ociperlimab - 2342597-93-5

MedChemExpress - Model Ociperlimab - 2342597-93-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Ociperlimab is a humanized IgG1 anti-TIGIT antibody. Ociperlimab binds to the extracellular domain of human TIGIT with high affinity (KD = 0.135 nM). Ociperlimab blocks the interaction between TIGIT and its ligands PVR or PVR-L2. Ociperlimab can be used in research of ...
CONTACT SUPPLIER

MedChemExpress - Model Trimetazidine - 5011-34-7

MedChemExpress - Model Trimetazidine - 5011-34-7

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Trimetazidine is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine triggers autophagy. Trimetazidine is also a 3-hydroxyacyl-CoA ...
CONTACT SUPPLIER

MedChemExpress - Model Hexamethylene bisacetamide - 3073-59-4

MedChemExpress - Model Hexamethylene bisacetamide - 3073-59-4

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Hexamethylene bisacetamide (HMBA) is a differentiation inducer and selective bromine domain inhibitor that can differentiate across the blood-brain barrier. Hexamethylene bisacetamide can induce tumor cell differentiation and inhibit cell proliferation, showing antitumor activity. Hexamethylene bisacetamide induces apoptosis by Notch1, Bcl-2 and p53 signaling pathways. In addition, Hexamethylene ...
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MedChemExpress - Model Trimetazidine dihydrochloride - 13171-25-0

MedChemExpress - Model Trimetazidine dihydrochloride - 13171-25-0

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Trimetazidine dihydrochloride is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine dihydrochloride is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine dihydrochloride triggers ...
CONTACT SUPPLIER

MedChemExpress - Model Rituximab (anti-CD20) - 174722-31-7

MedChemExpress - Model Rituximab (anti-CD20) - 174722-31-7

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Rituximab (anti-CD20) is an anti-CD20 chimeric monoclonal antibody used to treat certain autoimmune diseases and types of ...
CONTACT SUPPLIER

MedChemExpress - Model Tafasitamab - 1422527-84-1

MedChemExpress - Model Tafasitamab - 1422527-84-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Tafasitamab (XmAb5574) is an Fc-modified, humanized monoclonal antibody that binds to the human B-cell surface ...
CONTACT SUPPLIER

MedChemExpress - Model Treprostinil - 81846-19-7

MedChemExpress - Model Treprostinil - 81846-19-7

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Treprostinil (UT-15) is a potent DP1 and EP2 agonist with EC50 values of 0.6±0.1 and 6.2±1.2 nM, ...
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MedChemExpress - Model Fludarabine - 21679-14-1

MedChemExpress - Model Fludarabine - 21679-14-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Fludarabine (NSC 118218) is a DNA synthesis inhibitor and a fluorinated purine analogue with antineoplastic activity in lymphoproliferative malignancies. Fludarabine inhibits the cytokine-induced activation of STAT1 and STAT1-dependent gene transcription in normal resting or activated ...
CONTACT SUPPLIER

MedChemExpress - Model Pentostatin - 53910-25-1

MedChemExpress - Model Pentostatin - 53910-25-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Pentostatin (CI-825; Deoxycoformycin) is an irreversible inhibitor of adenosine deaminase with Ki of 2.5 ...
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MedChemExpress - Model (±)-10-Hydroxycamptothecin - 64439-81-2

MedChemExpress - Model (±)-10-Hydroxycamptothecin - 64439-81-2

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
(±)-10-Hydroxycamptothecin is an indole alkaloid that inhibits the activity of topoisomerase I and has a broad spectrum of anticancer ...
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MedChemExpress - Model Verteporfin - 129497-78-5

MedChemExpress - Model Verteporfin - 129497-78-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Verteporfin (CL 318952) is a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as age-related macular degeneration. Verteporfin is a YAP inhibitor which disrupts YAP-TEAD interactions. Verteporfin induces cell apoptosis[1]. Verteporfinis an autophagy inhibitor that blocks autophagy at an early stage by inhibiting ...
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MedChemExpress - Model Cilengitide - 188968-51-6

MedChemExpress - Model Cilengitide - 188968-51-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Cilengitide (EMD 121974) is a potent integrins antagonist with IC50s of 0.61 nM (ανβ3), 8.4 nM (ανβ5) and 14.9 nM (α5β1), respectively. Cilengitide inhibits the binding of ανβ3 and ανβ5 to Vitronectin with IC50s of 4 nM and 79 nM, respectively. Cilengitide inhibits TGF-β/Smad signaling, mediates PD-L1 expression. Cilengitide also induces apoptosis, shows antiangiogenic effect in the research ...
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MedChemExpress - Model Indirubin - 479-41-4

MedChemExpress - Model Indirubin - 479-41-4

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against chronic myelocytic ...
CONTACT SUPPLIER

MedChemExpress - Model Tetrahydrouridine - 18771-50-1

MedChemExpress - Model Tetrahydrouridine - 18771-50-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Tetrahydrouridine dihydrate is potent inhibitor of cytidine deaminase (CDA), which competitively blocks the enzyme's active site more effectively than intrinsic ...
CONTACT SUPPLIER

MedChemExpress - Model Deguelin - 522-17-8

MedChemExpress - Model Deguelin - 522-17-8

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Deguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-κB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1α, COX-2, and ...
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MedChemExpress - Model Degrasyn - 856243-80-6

MedChemExpress - Model Degrasyn - 856243-80-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Degrasyn (WP1130) is a cell-permeable deubiquitinase (DUB) inhibitor, directly inhibiting DUB activity of USP9x, USP5, USP14, and UCH37. Degrasyn has been shown to downregulate the antiapoptotic proteins Bcr-Abl and ...
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MedChemExpress - Model TD-198946 - 364762-86-7

MedChemExpress - Model TD-198946 - 364762-86-7

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
TD-198946, a thienoindazole derivative, is a potent chondrogenic ...
CONTACT SUPPLIER

MedChemExpress - Model Helichrysetin - 62014-87-3

MedChemExpress - Model Helichrysetin - 62014-87-3

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Helichrysetin is isolated from the flower Helichrysum odoratissimum. Helichrysetin is an ID2 (DNA binding inhibitor 2) inhibitor. Helichrysetin induces apoptosis. Helichrysetin has anti-tumor and antioxidant ...
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