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Express Gene Equipment Supplied In Germany
22 equipment items found
Manufactured by:MorphoSys AG based inPlanegg, GERMANY
Pelabresib (CPI-0610) is an investigational selective small-molecule designed to promote anti-tumor activity by inhibiting the function of bromodomain and extra-terminal domain (BET) proteins to decrease the expression of abnormally expressed genes in cancer. The compound has demonstrated a wide therapeutic window, with activity seen at a 48 mg ...
Manufactured by:Singleron Biotechnologies GmbH based inKöln, GERMANY
DynaSCOPE Single Cell RNA Dynamics Library Kit is the one-and-only commercial kit available that measures the rate and level of nascent RNA over a period of time in single ...
Manufactured by:ProBioGen AG based inBerlin, GERMANY
Typically, cell line development relies on the integration of transgenes anywhere into the genome. How active that spot is, is a matter of luck. Winning clones are identified in extensive screens. You, though, want to position your transgene where the action is to yield the best results for your product. ...
Manufactured by:Cerca Biotech based inBerlin, GERMANY
The Estrogen receptor 1 gene (ESR1) belongs to the family of steroid receptors. The protein is expressed intracellularly. It is a transcription factor regulating the expression of genes and is activated by estrogen. Estrogen receptors are overexpressed in about 70 % of all Breast Cancer cases. ...
Manufactured by:Singleron Biotechnologies GmbH based inKöln, GERMANY
This novel technology enables researchers, pathologists, food industries and fermentation businesses to study stochastical variations of gene expression in yeast population through single-cell sequencing with reliable and standardized results. ...
![Reaction Biology - Model ASH1L- [BRD] - Bromodomain Protein Assay](https://d32zuqhgcrpxli.cloudfront.net/eyJidWNrZXQiOiJlZS1maWxlcyIsImtleSI6ImZpbGVzLzExNTUzNy9pbWFnZXMvMTE1NTM3XzBfMjAyMTA0MTYwNDU3NTA3MTI0OTA5XzQwMC5qcGciLCJlZGl0cyI6eyJyZXNpemUiOnsiZml0IjoiY29udGFpbiIsImJhY2tncm91bmQiOnsiciI6MjU1LCJnIjoyNTUsImIiOjI1NSwiYWxwaGEiOjF9LCJ3aWR0aCI6MjQwLCJoZWlnaHQiOjE0NX19fQ== "Reaction Biology - Model ASH1L- [BRD] - Bromodomain Protein Assay")
by:Reaction Biology Corp. based inMalvern, PENNSYLVANIA (USA)
ASH1L is the human homolog of Drosophila Ash1, a Trithorax group protein. Like its counterpart in Drosophila, ASH1L has been found to play a role in the regulation of Hox gene expression. The ASH1L bromodomain displays strong binding to various Lys(Ac) residues in singly acetylated histone peptide microarrays (histones H1.4K74Ac, H2AK36Ac, H2BK85Ac, H3K56Ac, ...
by:Revvity Gene Delivery (formerly SIRION Biotech) based inHamburg, GERMANY
Adenoviral vectors offer high levels of transgene expression in broad cell types, including dividing and non-dividing cells. Adenoviral vectors are the method of choice whenever fast and transient gene expression for a very large gene or several genes is required, since the expression cassette ...
by:Reaction Biology Corp. based inMalvern, PENNSYLVANIA (USA)
Like its counterpart in Drosophila, ASH1L contains a SET histone methyltransferase domain and has been found to play a role in the regulation of Hox gene expression. Although the ASH1L SET domain has been shown in vitro to methylate histone peptides on lysine-4 of histone H3 (H3K4), ASH1L is an H3K36 methyltransferase both in vivo and in vitro with nucleosomes as ...
Manufactured by:provitro AG based inBerlin, GERMANY
Cultures based on cell monolayers have the advantage of reducing tissue complexity to a minimum. However, the lack of normal physiological cell-matrix interactions leads the cell metabolism and gene expression towards a dedifferentiated state. Compared to a monolayer, three-dimensional cultures are associated with a higher cell density, and nutrient supply ...
by:Reaction Biology Corp. based inMalvern, PENNSYLVANIA (USA)
In collaboration with the bioinformatics firm 4HF Biotech GmbH which is a bioinformatics firm specializing in cancer data mining to discover new anti-cancer drugs, we offer data mining for analysis of the genetic signature of tumor cell lines that are sensitive for a customer drug to reveal potential biomarkers. The Biomarker Analysis is based on the sensitivity profile of the customer compound ...
Manufactured by:Mediagnost Gesellschaft für Forschung und Herstellung von Diagnostika GmbH based inReutlingen, GERMANY
Adiponectin is a protein of 30kDa which exists in several multimeric forms. About 0,01% of the proteins in human serum are adiponectin. The ADIPOQ-Gen is the gene mostly expressed by adipocytes. In spite of that the serum adiponectin concentration is negatively correlated with body fat mass. The protein consists of 244 amino acids and has a globulary domain which ...
Manufactured by:HepaRegeniX GmbH based inTübingen, GERMANY
His laboratory identified Mitogen-Activated Protein (MAP) Kinase Kinase 4 (MKK4) as a key regulator of liver regeneration. Suppression of MKK4 gene expression by small RNA molecules demonstrated the regenerative capacity of hepatocytes even in severely diseased livers. 7 Prof. Zender and his group are important cooperation partners of HepaRegeniX still ...
Manufactured by:Singleron Biotechnologies GmbH based inKöln, GERMANY
FocuSCOPE is a high-throughput single cell multi-omics sequencing solution that can detect both genetic variants and transcriptome from the same single cells. Thus, FocuSCOPE® provided a tool to decipher the connection between genotype and phenotype at single cell ...
Manufactured by:Singleron Biotechnologies GmbH based inKöln, GERMANY
GEXSCOPE Single Cell V(D)J Kit enables simultaneous detection of T-cell or B-cell receptor gene expression, together with whole transcriptome expression at single-cell ...
Manufactured by:Atriva Therapeutics GmbH based inTübingen, GERMANY
The company’s lead drug candidate zapnometinib targets the intracellular Raf/MEK/ERK signaling pathway. This pathway is central for replication of many RNA viruses, such as the influenza virus, Hantavirus or respiratory syncytial virus (RSV) and also SARS-CoV-2, the virus that causes COVID-19. In influenza virus infected cells, the interaction of zapnometinib with MEK (MAPK/ERK kinase) ...
Manufactured by:MorphoSys AG based inPlanegg, GERMANY
EZH2 acts as an epigenetic writer and normally places one or more methyl groups on a histone protein, leading to the suppression of gene expression. Some cancers depend on an abnormal pattern of gene expression and re-direct EZH2 to genes that become abnormally repressed. Cancer cells with these abnormal ...
Manufactured by:InVivo BioTech Services GmbH a BRUKER Company based inHennigsdorf, GERMANY
Transient gene expression in mammalian cells provides reasonable amounts of recombinant proteins and antibodies which is sufficient for most applications. Nevertheless, when it comes to bulk productions for in vitro diagnostics or pre-clinical studies for biopharmaceutical development, the required amount of biological material often exceeds the yield that can be ...
Manufactured by:Agilent Technologies, Inc. based inSanta Clara, CALIFORNIA (USA)
Total Confidence qPCR delivering flexibility, precision, and performance. The AriaMx Real-Time PCR System is a fully integrated quantitative PCR amplification, detection, and data analysis system. The system design combines a state-of-the-art thermal cycler, an advanced optical system with an LED excitation source, and complete data analysis software. The instrument can hold up to six optics ...
Manufactured by:NeraCare GmbH based inFrankfurt, GERMANY
Melanoma is a serious form of skin cancer that begins in cells known as melanocytes. While it is less common than basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), melanoma is far more dangerous because of its ability to spread to other organs more rapidly if it not treated at an early ...
Manufactured by:Therawis based inMunich, GERMANY
Personalized medicine aims to identify patients who require treatment and subsequently select the right therapy based on individual factors and tumor characteristics, i.e. personalized medicine targets to identify the right patients for the right therapy. Prognostic biomarkers provide information on the risk of disease recurrence whereby predictive ones will inform the physician of the potential ...