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Genomics Redefines The Boundaries Of Fungal Genomics Equipment Supplied In Usa Massachusetts
29 equipment items found
by:Myeloid Therapeutics based inCambridge, MASSACHUSETTS (USA)
Retrotransposons are genetic elements that can replicate through reverse transcription of an RNA transposition intermediate. They contribute to structural changes and, more importantly, to gene regulation. Our proprietary RNA-based, retrotransposon-mediated gene-insertion technology (CREATE) has applications across gene editing and ...
by:Ginkgo Bioworks Inc. based inBoston, MASSACHUSETTS (USA)
We use our circular RNA platform to vastly accelerate understanding of regulatory elements involved in transcription. What we deliver is a range of promoters/enhancers of varying strength and specificity designed for expression at the right time and place. Why optimize transcription? Transcriptional control is the primary method of cellular control and can work over a 100,000-fold range. Other ...
Manufactured by:AMS Biotechnology (Europe) Ltd. based inAbingdon, UNITED KINGDOM
SKU: HD-902-HR. Size: 30 reactions. Species: Human. Tissue Type: Bladder. Storage: -20C. Shipping TempGel: ...
Manufactured by:SeQure Dx, Inc. based inWaltham, MASSACHUSETTS (USA)
GUIDE-seq and ONE-seq are used to nominate potential off-target editing sites in cellular models and free DNA, respectively. ONE-seq has the advantages that it can be used to assess adenine and cytosine base editors, it allows variant-aware analysis of multiple genomes simultaneously (thousands), and it detects a broader spectrum of off-target sites. Target cells or tissues are then tested to ...
Manufactured by:LGC SeraCare based inMilford, MASSACHUSETTS (USA)
The AccuPlex SARS-CoV-2 Molecular Controls Kit – Full Genome contains positive reference materials for the entire SARS-CoV-2 genome. Also includes negative materials targeting the human RNase P gene. It is designed to measure day-to-day performance of the assay, providing both a positive and a negative reference ...
Manufactured by:LGC SeraCare based inMilford, MASSACHUSETTS (USA)
The AccuPlex™ SARS-CoV-2 Verification Panel – Full Genome contains three different concentrations of positive reference material for the entire SARS-CoV-2 genome. Also includes negative reference material directed against the human RNase P gene. The panel is optimized for assay verification at installation by documenting test performance along the assay’s range enabling ...
Manufactured by:Obsidian Therapeutics, Inc. based inCambridge, MASSACHUSETTS (USA)
Our proprietary cytoDRiVE® platform leverages drug responsive domains (DRDs) to control protein function using an FDA-approved small ...
by:Vor Biopharma based inCambridge, MASSACHUSETTS (USA)
Our first multi-targeted Treatment System is comprised of VOR33-CLL1 multiplex-edited eHSC therapy and VCAR33-CLL1 multi-specific CAR-T therapy. Knocking out CD33 and CLL-1 through gene editing offers a promising new approach to treating patients with AML using our novel eHSC platform. Our research demonstrates that multiplex genome editing of allogeneic hematopoietic stem cells may represent ...
by:Sumitomo Pharma Oncology, Inc. based inCambridge, MASSACHUSETTS (USA)
DSP-5336 is a small molecule inhibitor against the binding of menin and mixed-lineage leukemia (MLL) protein. Menin is a scaffold nuclear protein that plays various key roles in biological pathways, including cell growth regulation, cell cycle control, genomic stability, bone development, and hematopoiesis.26,27 Binding of menin to MLL fusion and wildtype proteins leads to the upregulation of ...
by:Revvity Gene Delivery (formerly SIRION Biotech) based inHamburg, GERMANY
Adenoviral vectors offer high levels of transgene expression in broad cell types, including dividing and non-dividing cells. Adenoviral vectors are the method of choice whenever fast and transient gene expression for a very large gene or several genes is required, since the expression cassette has a total capacity of 7.5 kb. This provides space for flexible vector design with multiple transgenes ...
Manufactured by:Editas Medicine based inCambridge, MASSACHUSETTS (USA)
Genomic medicine is a developing field of medical research that harnesses recent advances in genetics to develop new medicines for diseases. In fact, we are at an inflection point where we are seeing the first real genomic medicines emerge to help patients. Advances in the scientific fields of cell therapy and gene therapy have paved the way for the success of gene editing, which in turn is now ...
Manufactured by:Thermo Fisher Scientific based inWaltham, MASSACHUSETTS (USA)
Invitrogen TrueCut HiFi Cas9 Protein is a high fidelity CRISPR Cas9 protein variant engineered to demonstrate superior off-target profiles, while preserving maximum on-target editing efficiency. TrueCut HiFi Cas9 Protein is ideal for applications that are sensitive to off-target events and when more precise editing is ...
by:Alexion Pharmaceuticals, Inc. based inBoston, MASSACHUSETTS (USA)
People with rare diseases often wait years to receive a proper diagnosis and many never receive one at all. RARE ANSWERS™ is a system of innovative and sustainable tools designed to help shorten the diagnostic journey and time to initiating treatment of children with a rare disease. Developed in collaboration with leading children’s hospitals and technology and data-science ...
Manufactured by:LGC SeraCare based inMilford, MASSACHUSETTS (USA)
The Seraseq Tumor Mutation DNA Mix v2 (AF7) HC is a multiplexed mixture of actionable biosynthetic DNA targets precisely blended with a single, well-characterized genomic background. This product is produced under rigorous design control and manufacturing practices to an allelic frequency of 7%, and is offered in a high concentration (HC) format at 25 ng/µL. Designed to assess the overall ...
by:Intellia Therapeutics, Inc. based inCambridge, MASSACHUSETTS (USA)
The first patient was dosed with our investigational genome editing treatment for transthyretin (ATTR) amyloidosis in November 2020. Our modular approach enables us to optimize the power and versatility of the CRISPR/Cas9 technology and, importantly, allows us to rapidly develop therapeutics for numerous diseases that currently have limited treatment ...
Manufactured by:Thermo Fisher Scientific based inWaltham, MASSACHUSETTS (USA)
Choose from a menu of verified real-time PCR assays to build your own custom Applied Biosystems TaqMan SARS-CoV-2 Mutation Panel, and get the results you need today, while preparing you for what’s to come. This scalable solution lets you run a few or hundreds of samples to identify one or many mutations—all on your current real-time PCR ...
Manufactured by:Bruker Corporation based inBillerica, MASSACHUSETTS (USA)
Optofluidic Technology is the Key to Faster Workflows and Deeper Data. See how opto-electropositioning (OEP) technology moves Cell Biology to light speed. Our technology combines precise cell processing, time-saving workflow automation, and rich, deep profiling. Watch this video animation, to see how Berkeley Lights advanced technology works. Welcome to the ...
by:Day Zero Diagnostics Inc. based inBoston, MASSACHUSETTS (USA)
While sample preparation technologies enable the whole genome sequencing of pathogens directly from clinical samples, once the samples have been sequenced there is a critical need for robust algorithms to interpret the sequencing data. Our computational methods take the raw genomic data as input and transform them into the diagnostic results that can serve infectious disease clinicians and ...
by:Intellia Therapeutics, Inc. based inCambridge, MASSACHUSETTS (USA)
Genome editing is efficient, precise and scalable. CRISPR/Cas9 genome editing can make permanent, precisely targeted changes in patients’ chromosomes and repair the underlying genetic mutation, whereas more traditional gene therapy typically involves introducing a non-permanent copy of a gene into patients’ cells. These attributes of CRISPR/Cas9 provide a significant therapeutic edge ...
by:Kephera Diagnostics, LLC based inFramingham, MASSACHUSETTS (USA)
Kephera is developing a test for Zika virus infection with support from a grant from the National Institutes of Health. Kephera’s Zika project is based on the identification of Zika-specific and Dengue-specific epitopes within the viral genome, from which an immunoassay will be developed in convenient and cost-effective ELISA format, and ultimately translated to point-of-care format. To ...