Sumitomo Metabolism Pathway Equipment & Supplies

1 equipment items found

Sumitomo - Model DSP-0390 - Emopamil-Binding Protein (EBP) Inhibitor

by:Sumitomo Pharma Oncology, Inc. based inCambridge, MASSACHUSETTS (USA)

DSP-0390 is an emopamil-binding protein (EBP) inhibitor. EBP is an endoplasmic reticulum membrane protein involved in cholesterol biosynthesis.47 When functional, EBP mediates de novo cholesterol synthesis for cell membrane structure and signaling, enabling aberrant growth of tumors.47-50 Inhibition of EBP causes an accumulation of its substrates zymostenol and zymosterol, which contributes to ...

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