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Therapeutic Development Equipment & Supplies In Netherlands
43 equipment items found
by:CrystalsFirst GmbH based inMarburg, GERMANY
FragAI is an automated workflow for generation of active molecules for therapeutics development using chemoinformatics, bioinformatics and machine learning. Our methodology uses the data flow from SmartSoak and FastForward output. The step of fragment hit expansion and evolution builds on validated fragment hits. ...
Manufactured by:ASC Therapeutics based inMilpitas, CALIFORNIA (USA)
Genome editing technologies enables permanent modifications to the genome by harnessing the activities of certain enzymes (e.g. nucleases and integrase) and invoking DNA repair mechanisms at specific locations in the genome. As a therapeutic modality, genome editing can correct a defective gene, disrupt a deleterious gene, or target a therapeutic gene to a ...
by:Neoclease based inBoston, MASSACHUSETTS (USA)
Neoclease is pioneering the future of precision medicine through advanced technology in synthetic biology and generative AI. By developing synthetic nucleases, the company enhances gene editing processes to achieve unprecedented specificity and efficacy. These enzymes are meticulously crafted using proprietary algorithms powered by state-of-the-art GPT neural networks, which are ...
Manufactured by:Genscript based inPiscataway, NEW JERSEY (USA)
cPass Neutralization Antibody Detection kit detects circulating neutralizing antibodies against SARS-CoV-2 that block the interaction between the receptor binding domain (RBD) of the viral spike glycoprotein with the ACE2 cell surface receptor. This kit would be instrumental in vaccine and therapeutic development as it is suitable for all antibody isotypes and ...
Manufactured by:Realize Therapeutics Corp. based inLake Bluff, ILLINOIS (USA)
SIBO is a condition related to excess numbers of bacteria in the small intestine, and can be linked to Irritable Bowel Syndrome, Research clearly shows that certain microbes are very effective at treating SIBO and related issues. Realize Therapeutics is developing formulas to address these health ...
Manufactured by:Entero Therapeutics, Inc. based inBoca Raton, FLORIDA (USA)
Capeserod is a selective 5-HT4 receptor partial agonist, which Entero Therapeutics is repurposing and developing for multiple GI conditions. Based on the biological evidence of expression of 5-HT4b receptor subtype in human GI tract, Entero Therapeutics believes that capeserod may directly or indirectly initiate the peristaltic or secretory ...
Manufactured by:Evox Therapeutics Limited based inOxford, UNITED KINGDOM
Evox’s proprietary protein engineering technology enables loading of protein therapeutics and tissue targeting moieties onto the surfaces of exosomes, which allows targeting and display of therapeutic proteins to an organ of ...
Manufactured by:PharmAbcine Inc. based inYuseong-gu, SOUTH KOREA
PharmAbcine’s fully human antibody library provides the diversity of antibody candidates for target antigens, ensuring highest success rates of developing therapeutic antibodies for various indications. Our unique and diverse antibody repertoires are constructed by recombination of V gene segments and DJ gene segments in human B-cell derived antibody heavy ...
Manufactured by:ProImmune Ltd. based inOxford, UNITED KINGDOM
Detecting and targeting specific MHC-peptide complexes is of material interest for understanding many disease conditions better and for developing novel therapeutic interventions. It has been very challenging to develop antibodies that bind selectively to an MHC-peptide combination over a more general MHC ...
Manufactured by:Neutron Therapeutics, Inc. based inDanvers, MASSACHUSETTS (USA)
Neutron Therapeutics has developed an accelerator-based, in-hospital neutron source to replace the previously required nuclear reactor. This source is composed of a 2.6 MeV electrostatic proton accelerator and a rotating, solid lithium target for generating neutrons. Neutron Therapeutics will provide this neutron source as part of a comprehensive ...
Manufactured by:Confo Therapeutics based inGhent/Zwijnaarde, BELGIUM
Confo Therapeutics is building a pipeline of drug candidates with the potential to transform therapeutic outcomes for patients with severe illnesses lacking disease-modifying ...
by:Curadigm based inParis, FRANCE
Curadigm’s technology was developed to address a critical challenge facing intravenously administered therapeutics: How can you efficiently deliver a drug to your tissue of interest without rapid clearance? To address this, we developed technology that reduces unwanted hepatic clearance, resulting in a temporary increase in blood ...
Manufactured by:SpliceBio based inBarcelona, SPAIN
The company has focused on the innovative application of inteins, a class of proteins that can perform protein splicing through biochemical reactions involving cleavage and bond formation. Historically, natural inteins presented several limitations, making them unsuitable for human therapeutics. SpliceBio's co-founders have overcome these barriers by developing ...
Manufactured by:Kiadis Pharma NV based inAmsterdam, NETHERLANDS
Accessing a new repertoire of targets. Two classes of molecule with therapeutic potential that are not currently addressed by antibody drugs are G-protein-coupled receptors and ion channels, largely because they display small epitopes not accessible to traditional antibodies and their sequence is often conserved and thus less likely to be ...
Manufactured by:Catalent, Inc based inSomerset, NEW JERSEY (USA)
GPEx cell line development technology is a proven technology that generates high-performance, highly stable, production cell lines. Virtually any cDNA (mAb and multigenic applications) can be inserted into cells. To date, over 600 different mAb and mAb fusions and over 160+ different recombinant proteins have been produced using the GPEx system, with 160+ clinical trials ...
by:AbCellera Biologics Inc. based inVancouver, BRITISH COLUMBIA (CANADA)
We search, decode, and analyze natural immune systems to find antibodies that our partners can develop into drugs that improve ...
Manufactured by:TxinnoBioscience Inc. based inYongin-si, SOUTH KOREA
RAS GTPase family has 3 members encoding KRAS, HRAS and NRAS proteins which are involved in controlling normal growth signal. RAS GTPases are also well-known oncogenes that drive tumorigenesis when mutation is ...
Manufactured by:Kalaris based inWaltham, MASSACHUSETTS (USA)
Kalaris Therapeutics is focused on developing innovative treatments for retinal diseases, aiming to reduce the burden of frequent clinical visits for patients with retinal neovascular and exudative conditions. Their lead product, TH103, is a fully humanized, recombinant fusion protein designed for intravitreal delivery as an anti-VEGF agent. ...
Manufactured by:Microviable Therapeutics SL based inGijón, SPAIN
Microviable Therapeutics is developing novel technologies and next generation biotherapeutic products by harnessing the treasure of the human microbiota generating innovative solutions that enable to address unmet challenges in human ...
Manufactured by:Entero Therapeutics, Inc. based inBoca Raton, FLORIDA (USA)
FW-EPI (adrulipase) is a recombinant lipase enzyme administered as an oral, non-systemic biologic capsule for the treatment of exocrine pancreatic insufficiency (EPI) associated with cystic fibrosis (CF) and chronic pancreatitis (CP). Adrulipase is derived from the Yarrowia lipolytica yeast lipase and is designed to break up fat molecules in the digestive tract of EPI patients so that they can be ...