Hummingbird -Model miRNAs -Liquid Biopsy Diagnostics for Early Disease Detection
MiRNAs are small, highly conserved, non-coding RNAs playing crucial roles in the regulation of virtually all aspects of living cells.
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early disease detection
biopsy diagnostic
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body fluid
liquid biopsy
neurology disease
disease diagnosis
MiRNAs have been implicated in a wide range of diseases – including different types of cancers, heart conditions and neurological diseases. They are promising candidates for diagnostic and prognostic biomarkers, as well as predictors of drug response. As non- or minimal invasive biomarkers from body fluids, they show a remarkable extracellular stability making them near ideal clinical biomarkers.
DYNAMICS
- Dynamic regulator of cell/tissue function
- Monitors physiology and/or pathology in real time
- Longitudinal monitor
SPECIFICITY
- Multiple markers
- Baseline steady in time
- Unaffected by other unrelated physiology e.g. exercise
APPLICATION
- Multiple diseases
- Primary diagnosis
- Disease/treatment monitoring
- Companion diagnostics
INSIGHT
- Origin of disease
- Immunological response
- Immune status