PhysioMimix - Model MPS LC12 - Liver Consumable Plate
Arranged in a multi-well format, the PhysioMimix™ MPS-LC12 plate has 12 independent bioreactors.
Three dimensional (3D) scaffolds, embedded in each of the wells, are continually perfused by cell culture medium during experiments.
The MPS-LC12 consumable plates are designed to create optimal conditions for primary human hepatocytes and non-parenchymal cells (NPCs). Human primary liver cells are cultured in 3D microtissues on an engineered scaffold which mimics the architecture of the liver capillary bed under perfusion. The MPS-LC12 plate can also be used to culture other tissue types, precision cut tissue slices or organoids in a perfused 3D format.
In conjunction with PhysioMimix OOC Systems, the MPS-LC12 consumable plate can be used for a wide range of applications such as:
- Disease modelling, e.g.: NAFLD/NASH, DILI, Hepatitis B
- Toxicology
- ADME
- Pharmacology
- Immuno-oncology
- Drug repurposing