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Nanoactive Technology
Conversion of Sirolimus drug into sub-micron sized particles; Nanocarriers created by encapsulation of sub-micron sized Sirolimus drug into highly biocompatible drug Carrier-phospholipid; Encapsulated Sirolimus is coated on stent and parts of balloon; Upon implantation of Abluminus NP at target site, Nanocarriers with Sirolimus drug from stent and parts of balloon get transferred to the vessel wall following the principle of co-efficient diffusion; Upon body pH variation, Nanocarriers mimics the body lipids and liberates Sirolimus; The sub-micron sized Sirolimus drug particles penetrate the deepest layer of the vessel over a period.
- Better in-tissue bioavailability of drug
- Reduces drug dose
- Effective drug transfer to the deepest layer of the vessel
- Protect drug by encapsulation- reduced in-transit drug loss
ABLUMINAL COATING
Drug is coated on the abluminal side only.
Leading to mono directional drug release & less systemic exposure of drug which leads to faster healing
FUSION COATING
Drug is coated on stent as well as exposed parts of balloon & coated on the proximal and distal ends.
Helps to address the entire disease area of lesion and address focal restenosis and edge restenosis.
POLYMER FREE NANO CARRIER DRUG DELIVERY
Designed for acute as well as sustained drug transfer in arterial wall – leading to less chronic inflammation and improved vascular healing.
POLYMER FREE COATING
Proposed the shorter DAPT which helps to reduced bleeding risk in patients with high bleeding risk