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Model STALIF C-Ti - No-Profile® Anterior Cervical Integrated Interbody System
FromCentinel Spine
Based on the successful STALIF C® device, STALIF C-Ti™ incorporates a novel, titanium-surfaced PEEK Integrated Interbody™ design that is raising the Gold Standard of cervical interbody. The Ti-ACTIVE™ surface provides a three-dimensional texturized surface that is microporous with hydrophilic properties, to facilitate human mesenchymal stem cell (hMSC) attachment and proliferation as demonstrated by pre-clinical testing performed on representative PEEK coupons with Ti-ACTIVE surface.2 During manufacturing, commercially pure titanium (CP Ti) is applied to the PEEK cage by a plasma spray to create our Ti-ACTIVE devices. The unique CP Ti surface system utilizes a robotic applicator, enabling the creation of a high-quality, reproducible titanium surface.3 Ti-ACTIVE was tested for mechanical integrity and the results exceeded the FDA requirements for shear and tensile strength for metallic spray surfaces.4
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Texturized Titanium Surface
SEM image (2,000x magnification) of the surface of a standard PEEK implant (left) and a titanium-applied PEEK implant (right). Unlike standard PEEK, the PEEK with titanium surface provides a 3-D microporous environment conducive to cell attachment and cell migration, seen by cytoplasmic expansions of the cultured cells, as highlighted in purple.
Cell Proliferation
SEM image (2,000x magnification) showing cellular interaction allowing human mesenchymal stem cells (hMSCs) to communicate when receptors and markers bind on a Ti-ACTIVE™ surface. Cell to cell interactions are vital in the promotion of cell adhesion and later the function of the cell to differentiate and proliferate, as highlighted in yellow. Ti-ACTIVE™ offers an optimized surface topography enabling cellular migration, cellular interaction, and cellular attachment to the surface as observed on representative STALIF® coupons with Ti-ACTIVE™ surface.2
By preserving its PEEK roots, STALIF C-Ti™ exhibits a modulus of elasticity similar to bone. In doing so, the device presents a reduced risk of subsidence relative to all-titanium cages.5 Additionally, STALIF C-Ti™ continues to maintain the radiolucent advantage of PEEK.
Radiolucent Advantage
The STALIF C-Ti™ device maintains the radiolucent advantage of PEEK, making it easier to assess post-operative development of fusion mass during follow-up.7 The Ti-ACTIVE™ surface allows for radiographic visualization of the graft-endplate contact. Images show radiographs of STALIF C-Ti™ in Anterior/Posterior view (left) and Lateral view (right).
Osteo-Similar Modulus
PEEK is less rigid than titanium. PEEK`s elastic modulus is closer to that of cortical bone (see chart above).4 Compared to all-titanium cages, PEEK cages have been shown to be six times less likely to experience subsidence.6