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Auro - Model PBS VAX - Preclinical-Stage Therapeutic Vaccines for HBV
Auro Vaccines has also developed a GeneVax prime/VesiculoVax boost therapeutic vaccine that targets all eight HBV genotypes for use as an adjunct to drug therapy.
Program Status:
Several candidate GeneVax™ prime/VesiculoVax™ vaccine combinations have been tested in small animals for immunogenicity and down-selection of the lead vaccine candidates has been completed. Further development of this candidate is currently on hold and is available for out-licensing or co-development.
Unmet Medical Need:
HBV is the most common cause of serious liver disease in the world. Worldwide over 2 billion people have been infected and 400 million remain chronically infected. More than 1 million people die each year from HBV and its complications. The Auro Vaccine GeneVax™ prime/VesiculoVax™ boost therapeutic HBV vaccine is designed to be used in conjunction with drug therapy to cure HBV infection.