Eutilex -Model EU301(MVR CAR-T) -Relapsed and Refractory B Cell Leukemia and B Cell Lymphoma

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MVR CAR-T can be used against HLA-DR positive cancer, as well as B cell malignancy. The epitopes recognized by HLA-DR are not shed or internalized, enabling stable binding to human lymphoma cells. MVR CAR-T can also be used in patients who relapse after CD19 CAR-T treatment. Reduction of cytokine secretion due to selective killing of tumor cells.

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Indication
B-cell precursor ALL
Diffuse large B-cell lymphoma (DLBCL)

Target /Drug class
HLA-DR expressing cancer cell / CAR-T

Development Stage
Non-clinical