Osteochondral lesions can occur from an acute traumatic injury to the knee or an underlying bone disorder. They impact the lives of hundreds of thousands of patients every year. There is a clear and enduring unmet need for a true regenerative solution that can be delivered in a single procedure, in an outpatient setting and at an affordable price.

Just as with LDGraft, our goals for Chondro3 are both ambitious and based on a product profile with no room for compromise.

To succeed, we believe the graft should:

Promote the repair of the damaged cartilage and underlying bone at the same rate.
Allow seamless integration of the graft into the local host tissues.
Have significant porosity to allow for cells and nutrients to move into the graft and for waste to be removed.
Consistently drive the regeneration of long-lasting hyaline cartilage (chondrogenesis) and bone repair (osteogenesis) by incorporating powerful signalling mechanisms without the need to adds cells or growth factors.
Mimic evolution by having a tidemark transition layer that will offer protection to the cartilage layer from:
1. Bone overgrowth and
2. The destructive shear forces at the interface between the hard, bony tissue and the rubbery cartilage layer.

With multiple peer-reviewed, published pre-clinical data showing the consistent production of hyaline cartilage, we are very excited by the significant opportunity that Chondro3 brings.

Chondro3 - Revolutionary, Biomimetic Graft for Osteochondral Lesions