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CRYOTEK - Tissue Cryopreservation Technology
TissueTech’s initial research and development efforts were focused on the development of its cornerstone cryopreservation technology – CRYOTEK. The CRYOTEK process is a proprietary tissue-processing method that preserves the innate biological and structural integrity of the natural placental tissue and therefore preserves and delivers the anti-inflammatory, anti-scarring, and anti-angiogenesis properties of that matrix. In particular, the CRYOTEK process is the ONLY method proven to effectively retain the Heavy Chain Hyaluronic Acid/Pentraxin3 (HC-HA/PTX3) complex, which has been demonstrated to orchestrate an environment that promotes regenerative healing. CRYOTEK-processed tissues are also the only available placental allografts that have been shown to be equivalent to fresh placental tissue and superior to other available placental allografts that are provided in a dehydrated state.
The clinical benefits of the CRYOTEK process have been demonstrated in more than 300 peer-reviewed publications. By devitalizing the resident living cells, CRYOTEK minimizes the risk of an immune reaction while preserving key components of the extracellular matrix: 1,2,3
- Collagen (types I, III, IV, V and VI)
- Fibronectin
- Laminin
- Hyaluronic Acid
- Proteoglycans
- Growth Factors
- HC-HA/PTX3 (immuno-signaling complex)
Cryopreserved umbilical cord and amniotic membrane have been demonstrated to promote critical healing actions:
- Modulate inflammation to orchestrate a regenerative healing environment
- Decrease scarring
- Reduce pain associated with inflammation