toxomiR - microRNA Biomarkers of Toxicity

The term toxomiR refers to a selection of 19 microRNAs that are enriched in various tissues. Toxicant-induced changes in the transcription and secretion of toxomiRs are highly sensitive to toxic effects occuring in the liver, kidney, central nervous system, heart, muscle, lung, pancreas, vascular injury, and due to endocrine disruption. ToxomiRs can be analyzed in serum or plasma. This recently published review, gives detailed insight into the clinical utility of circulating microRNAs as biomarkers of toxicity.