Pishtaz -Model PT-AFP-96 -Tumor Marker Elisa Kit
Alpha-Feto Protein (AFP) is a 70,000 kDa glycoprotein molecule which is closely related to human albumin both genetically and structurally. AFP is produced initially by the fetal yolk sac in small quantities and then in large quantities by the fetal liver as the yolk sac degenerates. The peak concentration in the fetal serum is approximately 3,000,000 ng / ml, and it is reached at this level within 9 weeks gestation. The concentration then declines steadily to about 20,000 ng / ml at the end of term.
- 75 min Total Time
- Antigen Capture Assay Type
- 96 Tests Package Size
- 1 ng/ml Minimum Detection
Maternal AFP is first detectable at 5 ng / ml in serum at about 10 weeks gestation. The concentration increase about 15 % per weeks to a peak of approximately 180 ng / ml at about 25 weeks. Measurement of AFP concentration in maternal serum in the second trimester of pregnancy and amniotic fluid used widelyto screen for prenatal open neural tube defect (NTD) in the fetus. In addition determination of AFP concentration is helpful in the diagnosis and management of patients with primary hepatoma, yolk sac carcinoma and testicular and presacral teratocarcinomas.
Factor: Value
- Assay Type: Antigen Capture (Antibody Sandwich)
- Chromogen Substrate: Ready to Use
- Conjugate: Ready to Use
- Control: Two Vials: Negative and Positive
- Incubation time: (Room Temperature) 30 + 30 + 15 min
- Standards: ng/ml 0 , 5 , 20 , 50 , 100 , 200
- Required Samplers: μl 10 , 100