ChIP Sequencing (ChIP-Seq) Service
Chromatin immunoprecipitation (ChIP) offers an advantageous tool for studying protein-DNA interactions and can be used to determine whether a specific protein binds to a particular sequence of a gene, such as the target sequence of a transcription factor or to compare the levels of histone methylation associated with a specific gene promoter region between normal and diseased tissues. Identifying the genetic targets of DNA binding proteins and revealing the mechanism of protein-DNA interaction is crucial for understanding cellular processes.
Map genome-wide histone modifications with EpiGentek’s comprehensive chromatin immunoprecipitation sequencing (ChIP-Seq) platform. Optimized buffers and protocol allow minimal ChIP background and increased sensitivity and specificity of the ChIP reaction.
- All kits used in our ChIP-Seq services are commercially available with our ChIP-Seq Workflow.
- Highly efficient enrichment of targeted DNA. Enrichment ratio of positive to negative control > 500.
- High sensitivity and flexibility allows both non-barcoded (singleplexed) and barcoded (multiplexed) DNA library preparation.
- Delivery of high-quality publishable data.
- Receive full deliverable package including Illumina FASTQ raw sequencing files, FastQC quality control insight, Bismark read mapping, Peak calling, peak annotation and differential binding analysis.