Immune Repertoire Profiling Service (TCR/BCR)
Immune Repertoire often represents an individual’s current immuno- logical status, whether healthy, vaccinated, diseased or infected. Only the high-throughput NGS analysis could comprehensively profile an individual’s immune repertoire. Celemics presents Immune Repertoire Profiling Service, providing effective data acquisition, integration, and interpretation for the customers.
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Features & Benefits
Quantitative analysis of the library diversity
- NGS-based analysis of complex antibody library consisting of millions (106 ~ 1012) of sequences in a single experiment
- Analysis of immunoglobulin and T-cell receptor repertoire analysis of BCR/TCR for each clone
- Frequency analysis of individual antibody clones within the library, identifying major and minor clones
- Tracking of clonal frequencies for each sample
- For antibody discovery, analysis of library diversity according to its panning degree enabling monitoring changes in clonal frequency
- Minimized omission of potentially significant antibody clones
- Analysis of immune repertoire characteristics from blood sample and monitoring of each clone
- Various analysis options for immune system studies
- Perform the experiment with drastically reduced time and cost enabled by the advanced technology of MSSIC developed from Celemics
- Support various types of BI data analysis
- Celemics’ proprietary BI analysis pipeline provides the various, visible, and easy to read results for customer’s antibody libraries.
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