Antigen Presenting Services
5 services found
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
To accelerate the development of cancer immunotherapy, it is essential to systematically identify tumor antigens that are truly tumor-specific, patient-shared, stably expressed (i. e., cloned) and immunogenic in all malignant cells. Immunopeptidomics is a large-scale and in-depth approach capable of identifying and quantifying the presented human leukocyte ...
Manufactured by:PharmAbcine Inc. based inYuseong-gu, SOUTH KOREA
The dual target antibody platform technology of PharmAbcine is based on the fully human antibody candidates selected from HuPhage biopanning process. Depending on antigen presentation patterns on target cell types and the related drug MOA, various bispecific platforms (DIG-body, PIG-body and TIG-body) are adopted in our antibody engineering strategy. Currently, ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Autophagy has an important role in diverse physiological processes such as adaptation to nutrient starvation, cell death, embryonic development, energy metabolism, and antigen presentation, among other events. Moreover, autophagy has been highlighted as a crucial component of pathological processes such as cancer, hypoxia, pathogen infection, and ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Functionally, cDCs include two states: immature and mature. Immature DCs are professional in uptaking and processing antigens, and mature DCs are specialist in antigen presentation. It has been observed that immature cDCs can induce immune tolerance, while mature cDCs induce Th2 or Th1 immune responses. ...
by:Istari Oncology Inc. based inMorrisville, NORTH CAROLINA (USA)
The tumor environment contains all the ingredients needed to mount an anticancer immune response—tumor antigens, antigen presenting cells (APCs, including tumor-associated macrophages [TAMs] and dendritic cells), and T cells—but activation of the immune system to generate that antitumor response is complex and multifaceted. By ...