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Ozgene Genomics Redefines The Boundaries Of Fungal Genomics Services Available In In Australasia
3 services found
Manufactured by:Ozgene Pty Ltd. based inBentley DC, AUSTRALIA
Knock-in mice have an insertion in a specific locus in order to produce genetically modified mice for customised research purposes. Reporter genes, human genes, related genes from the same organism, or point mutations can be introduced into the protein-coding region of a gene to produce knock-in mice. The difference between the knock-in and knockout approach is that knock-in mouse models are ...
Manufactured by:Ozgene Pty Ltd. based inBentley DC, AUSTRALIA
The targeted transgenic mouse approach uses gene targeting by means of homologous recombination in embryonic stem (ES) cells. The transgene cDNA is knocked into a ‘safe habor’ locus in the mouse genome to generate transgenic mice with a predictable expression pattern without disturbing endogenous gene activity. Safe harbor loci have been utilised in the mouse to investigate gene ...
Manufactured by:Ozgene Pty Ltd. based inBentley DC, AUSTRALIA
Humanized mice broadly refers to mice expressing human genes via transgenesis to gain relevant insights in the in vivo context for the understanding of human-specific physiology and pathology. Whilst many basic biological insights have been obtained from mouse studies, there are limitations to mouse models when investigating human biology. There are components of mouse biology systems that are ...