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Phenotype Services In Latin America
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Manufactured by:Ozgene Pty Ltd. based inBentley DC, AUSTRALIA
These mouse models allow researchers to gain insight into how the loss of the gene affects physiology, behavior and disease development. Observing the characteristics of a knockout phenotype can also help researchers understand human gene expression and genetic ...
Manufactured by:Ozgene Pty Ltd. based inBentley DC, AUSTRALIA
The targeted transgenic mouse approach uses gene targeting by means of homologous recombination in embryonic stem (ES) cells. The transgene cDNA is knocked into a ‘safe habor’ locus in the mouse genome to generate transgenic mice with a predictable expression pattern without disturbing endogenous gene activity. Safe harbor loci have been utilised in the mouse to investigate gene ...