Nuclear Receptor Activation Services

Screening for nuclear receptor activation is a widely used and accepted practice to predict adverse drug effects and drug-drug interactions. Moreover, assessing nuclear receptor activation meets the latest FDA guidance for industry on Drug-Drug Interactions. Receptor activation screening services using Puracyp’s proprietary cell lines are available to identify NCEs that have the potential to activate human, rat, mouse, dog or monkey SXR/PXR, AhR and CAR.