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Autoimmune Product Applications In Europe
10 applications found
High-throughput analysis of immune repertoires has contributed to the elucidation of mechanistic underpinnings of autoimmunity, driving the development of novel therapies and better ...
ByEnpicom B.V. based in s-Hertogenbosch, NETHERLANDS
Rheumatoid Arthritis (RA) is a common systemic autoimmune disease affecting between 0.5-1% of the adult population. RA is characterised by inflammation of the synovial joints which can lead to progressive joint destruction and consequently impair quality of life. ...
ByAxis-Shield Diagnostics Ltd. based in Dundee, UNITED KINGDOM
Discover autoantigens in autoimmune diseases, delineate new candidate biomarkers. Autoantibodies are present in the blood of all healthy individuals. However, when directed at high levels against protein targets in specific tissues, autoantibodies can be a major cause of autoimmune diseases. They are also important biomarkers for diagnosis of these conditions. ...
ByCambridge Protein Arrays Ltd. (CPAP) based in Cambridge, UNITED KINGDOM
Downregulating the immune response is necessary for the treatment of autoimmune diseases. In this aspect, the APO2L/TRAIL ligand is a key intermediate in immune cascades and is secreted in exosomes in natural conditions. ...
ByNanovex Biotechnologies based in Llanera, SPAIN
The two main types of arthritis are: osteoarthritis, usually caused by normal wear and tear of the joint rheumatoid arthritis, one of the most common autoimmune diseases. Other types of arthritis can be caused by uric acid crystals, infections or even an underlying disease such as psoriasis or lupus ...
ByNeopharmed Gentili S.p.A. based in Milano, ITALY
It holds great promise for the treatment of autoimmune diseases, cancer, and the prevention of transplant ...
ByNanovex Biotechnologies based in Llanera, SPAIN
By modifying the composition of the microbiota with probiotics, we may help to mitigate and solve upper respiratory, genitourinary or gastrointestinal tracts and periodontal infections, as well as dysbiosis issues related to fertility, premature births, dermatology, autoimmune diseases, and many more. The key is to choose the appropriate strain and dosage for each therapeutic target. ...
ByZinereo Pharma based in Pontevedra, SPAIN
Monoclonal antibodies (mAbs) are used to treat patients in a variety of conditions such as infectious disease, cancer, and autoimmunity. Discovery of therapeutic antibodies is a laborious process, that depends on high-throughput screening of antibody candidates to determine antigen specificity. ...
ByEnpicom B.V. based in s-Hertogenbosch, NETHERLANDS
The concept behind protein arrays is the immobilisation of sets of proteins, up to very large numbers, on solid supports, to perform miniaturised, multiplexed binding assays with a variety of potential ligands or interactants (see powerpoint presentation on right). HuProt v4 human proteome arrays as used at CPA comprise full length human proteins, many of which will retain their native conformation. HuProt arrays can be distinguished from arrays of peptides, used primarily to identify linear epitopes, or protein ...
ByCambridge Protein Arrays Ltd. (CPAP) based in Cambridge, UNITED KINGDOM
Dysregulation of immune cell functions can result in many serious and fatal diseases that require re-modulating the immune cells and restoring their normal response. Monitoring of immune cells while interacting with self-cells, pathogens, and cancer promotes our understanding of immune response or its failure ...
ByTelight based in Brno, CZECH REPUBLIC