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Brain Blood Product Applications In Europe
5 applications found
Kirkstall’s Quasi Vivo® system aims to establish and optimise a human in vitro 3D Blood Brain Barrier (BBB) in an effort to identify important mechanistic pathways for successful biomarker analysis, drug delivery and toxicity ...
ByKirkstall Ltd. based in York, UNITED KINGDOM
Functional ultrasound (fUS) is utilized in resting-state functional connectivity mapping as a technique to study intrinsic brain networks by detecting blood flow fluctuations. fUS boasts a higher spatial and temporal resolution compared to BOLD fMRI and provides greater sensitivity, making it effective in examining neuropsychiatric disorders and aiding early diagnosis. The device generates connectivity matrices both in 2D and 3D quickly, analyzing a single coronal plane or ...
ByIconeus based in Paris, FRANCE
The delivery of therapeutical compounds such as RNA drugs into the brain presents the challenges of RNA preservation and the crossing of the blood brain barrier. Exosomes loaded with the specific siRNA sequences and marked with the neuron specific RVG peptide show specific accumulation in neurons, microglia and oligodendrocytes in the brain, effectively reducing genetic expression. This is a potential approach for brain diseases ...
ByNanovex Biotechnologies based in Llanera, SPAIN
The trespassing of the blood brain barrier is a challenge for the treatment of central nervous diseases such as Alzheimer, Parkinson, stroke, or cancer (glioma). ...
ByNanovex Biotechnologies based in Llanera, SPAIN
In this example, the aggregation of magnetic nanoparticles labeled with DiR is monitored in real time. Tumor microvasculature is labeled using ...
ByMauna Kea Technologies based in Paris, FRANCE