Autoimmunity Articles & Analysis: This-Year
14 articles found
However, the same proteolytic activity that protects against pathogens can, when unregulated, contribute to tissue injury, autoimmune inflammation, and chronic disease progression. In recent years, recombinant ELANE protein has become an indispensable tool for researchers studying neutrophil function, protease regulation, and disease mechanisms, particularly in pulmonary, ...
Dysregulation of ubiquitination is a hallmark of numerous human diseases, including many cancers, neurodegenerative disorders like Parkinson's and Alzheimer's, and autoimmune conditions. How We Study the 'Ubiquitome': Ubiquitinated Proteomics Analysis Given its central role in health and disease, understanding which proteins are ubiquitinated, when, and how, is a major goal for ...
Tissue cross-reactivity studies play an essential role in the understanding of immune responses, particularly in the context of autoimmunity, transplant rejection, and vaccine development. These studies aim to identify whether antibodies or T cells generated against a particular antigen react with similar proteins found in different tissues, which can lead to unintended effects ...
These proteins are vital for treating conditions such as cancer, autoimmune diseases, and infectious diseases. Beyond therapeutic uses, recombinant proteins are instrumental in research and diagnostics. ...
These chemokines protein allows researchers to study the functional dynamics of chemokine-receptor interactions in controlled environments, facilitating the development of targeted therapies for a range of diseases, including cancer, autoimmune disorders, and chronic inflammatory conditions. One of the most significant applications lies in cancer immunotherapy. ...
Their highly specific interactions with biological targets offer unprecedented precision in treating autoimmune disorders, cancers, and genetic conditions. However, their structural complexity presents unique manufacturing challenges, requiring specialized bioprocessing techniques, cold chain management, and sophisticated analytical methods. ...
In recent years, the field of antibody drug design has become increasingly significant in the realm of therapeutic development, driven by the need for more effective and targeted treatments for various diseases, including cancer, autoimmune disorders, and infectious diseases. Antibodies, which are proteins produced by the immune system, have the ability to specifically recognize ...
Applications of Single-Domain Antibodies Single-domain antibodies have a wide array of applications across multiple fields: Therapeutics: They are being explored as potential treatments for various diseases, including cancer, infectious diseases, and autoimmune disorders, due to their ability to specifically target antigens. ...
Versatile Applications: This panel can be applied in various research settings, including cancer immunology, autoimmune diseases, infectious diseases, and neuroinflammation. It helps elucidate the roles of specific cytokines and chemokines in disease mechanisms and therapeutic responses. ...
By measuring cytokine levels, researchers can gain insights into the pathogenesis of infectious diseases and the effectiveness of potential treatments. Autoimmune and Inflammatory Diseases: Cytokines are central to the development and progression of autoimmune and inflammatory diseases. ...
As a result, PROTACs have emerged as a promising strategy in various fields such as oncology, neurodegenerative disorders, and autoimmune diseases. The Role of Discovery Services Discovery services play a critical role in the early stages of PROTAC development. ...
This approach is especially beneficial for investigating diseases with immune dysregulation, such as cancer, autoimmune disorders, or infectious diseases, where multiple cytokines orchestrate pathological processes. ...
Understanding the immune system is fundamental to advancing biomedical research, especially in areas such as cancer, autoimmune diseases, and infectious diseases. Mouse models play a pivotal role in this field, as their immune system shares many similarities with that of humans. ...
This characteristic makes hMSCs a promising candidate for treating autoimmune diseases and minimizing tissue rejection in transplant scenarios. ...