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Biological Sample Articles & Analysis
42 articles found
Why Their Analysis is Critical Because sterols are central to so many biological processes, the ability to accurately measure them is paramount. ...
In the realm of biological research, the ability to accurately observe and analyze cellular components is paramount. ...
Following freezing, the lung tissue is sectioned using a cryostat, a specialized apparatus that allows for precise slicing of frozen samples. Sections are typically cut at thicknesses ranging from 5 to 20 micrometers, depending on the intended analysis. ...
Together, these molecules orchestrate complex biological processes, including cell growth, differentiation, apoptosis, and migration. ...
They regulate inflammation, immunity, and hematopoiesis, making them essential for understanding various biological processes and disease mechanisms. For researchers working with rabbit models, the ability to accurately measure cytokine levels is vital. ...
Techniques for NAD/NADH Analysis Accurate analysis of NAD/NADH is challenging due to their instability and low abundances in biological samples. However, recent advances in analytical technology have greatly improved the precision and efficiency of these measurements. Common approaches include: High-Performance Liquid Chromatography (HPLC): This is a reliable and ...
A Luminex Cytokine Panel allows the simultaneous quantification of multiple cytokines, chemokines, and growth factors in a single sample. This multiplexing ability is critically important for researchers analyzing complex biological pathways, immune responses, and disease biomarkers. ...
Glycobiology, the study of carbohydrates and their biological functions, relies heavily on the ability to analyze large-scale carbohydrate interactions. ...
One of the remarkable properties of cytokines is their multipotency; a single cytokine can act on multiple cell types, influencing various biological responses. Additionally, there is often overlap in the functions of different cytokines, meaning that two or more cytokines can produce similar biological effects. ...
Peptides are short chains of amino acids linked by peptide bonds and are crucial in many biological functions. While proteins, composed of longer chains, execute complex and diverse roles in biological systems, peptides often function as hormones, neurotransmitters, or enzymes, regulating various physiological processes. ...
Discover how matched tumor-normal sequencing can help clinical researchers detect the somatic origin of variants with certainty. In the era of precision oncology, it has become increasingly common for patients diagnosed with cancer to undergo tumor sequencing. Identifying the mutations that make up a tumor’s genomic landscape can help guide selection of targeted therapies and inform ...
Differentially expressed proteins refer to proteins that show significant changes in their expression levels in different biological samples or under different treatment conditions. Observing such differential expression is crucial for understanding cellular physiology and disease mechanisms. ...
These probes are specifically designed to target and bind to the genetic material within CAR-T cells, enabling researchers to accurately track and monitor their presence in biological samples. The high specificity and sensitivity of the CABR™ ISH probes make them invaluable in studying the localization, distribution, and persistence of CAR-T cells in ...
Among them, glycoproteins are an essential biomarker that plays a key role in many biological processes, including disease onset, progression, and treatment response. ...
These techniques can separate, identify, and quantify collagen and its hydrolysis products in the samples.Common methods for collagen content determination include:1. Sample PreparationCollagen is extracted from the sample and preprocessed by centrifugation, filtration, or using Solid Phase Extraction (SPE) to remove impurities and purify the collagen.2. ...
Protein Target Quantification aims to accurately measure the abundance of specific proteins in biological samples. It has the advantages of high throughput, accuracy, and reproducibility. Using early data from differential proteomics/transcriptomics/genomics analysis, this method has validated biomarkers in large biological ...
Metabolomics presents several challenges that must be addressed to ensure reliable and reproducible results: Sample Complexity: Biological samples used in metabolomics, such as blood, urine, tissues, or cells, are inherently complex. ...
Bile acid analysis involves the quantification and profiling of these compounds within biological samples such as blood, urine, or feces. By delving into the composition and concentration of bile acids, researchers and clinicians gain valuable insights into various aspects of health and disease. ...
When studying gene expression, researchers often compare gene expression profiles between different biological samples or experimental conditions, such as healthy and diseased tissues, treated and untreated cells, or different developmental stages. ...
When studying gene expression, researchers often compare expression profiles across different biological samples or experimental conditions, such as healthy and diseased tissues, treated and untreated cells, or different developmental stages. ...