Biologically Active Material Articles & Analysis
18 articles found
Introduction Good Manufacturing Practice (GMP) cell banks play a crucial role in the biopharmaceutical industry, serving as foundational repositories of cell lines used for the production of therapeutic biological products. Characterization of these cell banks is essential to ensure the safety, efficacy, and consistency of the biopharmaceuticals derived from them. ...
For example, through carboxylic acid functional groups, PEGs can covalently bind to drugs, targeting ligands, or other biologically active molecules, thus enabling drug-targeted delivery and controlled release. ...
The cryogenic process is a method of freezing and storing samples that involves cooling the temperature of biological materials to stop normal cellular processes and prevent sample degradation for long-term storage. The cryogenic process and cryo storage are ideal solutions for the storage of biological samples and ensuring cell viability over time.Storing a sample under cryogenic conditions ...
Polyethylene glycol (PEG) is a suitable material for biological applications because it does not normally elicit an immune response. ...
Following the coronavirus emergency, surgeries and medical offices shall be reorganised to work safely. One of the first safety measure to adopt concerns suction of aerosol potentially infected. ...
ByAirsafe
Factors Affecting the Stability of Pharmaceutical Preparations Many factors affect the stability of drugs, for example, each active ingredient in the drug, each excipient in the preparation, packaging materials, and storage environments such as temperature, humidity, light, pH and air. ...
Due to its biological inertness and good biocompatibility, polyethylene glycol (PEG) has a wide range of applications in the pharmaceutical industry, biological materials, cosmetics, and analytical science. A number of compounds, such as proteins, peptides, oligonucleotides, drugs and liposomes, after being modified by PEG covalent bonding, can effectively extend the circulation time in the body, ...
Complex wounds often involve exposed deep structures of the dermal layer, requiring prompt wound closure and tissue reconstruction. It is essential to quickly assess the defect and identify the most effective treatment method for optimizing the patient’s experience and outcome. Often, dermal substitutes are selected as a surgical option for temporizing the wound bed while also facilitating ...
These benefits include: Robust in the presence of infection [1] Unlike biologics, NovoSorb BTM’s synthetic composition does not provide a food source for bacteria Designed to minimize scarring and contracture [1] NovoSorb BTM facilitates the body’s ability to regenerate the dermis Cost-effective alternative to biologics NovoSorb BTM ...
Bioceramic materials have a long history of being used to repair human hard tissues, from biologically inert materials (such as alumina and zirconia, etc.) to biological materials that are both biologically active and degradable (such as phosphate and silicate bioceramics, ...
ByMatexcel
Keywords: Bioengineered human acellular vessel; Biologic graft; Infected vascular graft; Vascular bypass Prosthetic vascular graft infections are a challenging complication with an incidence of 0.5% to 6% after surgical bypass.1 Prosthetic vascular graft infections are often treated with prosthetic graft excision and replacement with more infection-resistant ...
SARS-CoV-2 detection workflow in wastewater Monitoring wastewater for SARS-CoV-2 – or Coronavirus as it is more commonly known – can be a valuable data resource for an effective COVID-19 management. However, there are several challenges involved in detecting biological parameters in wastewater. Fortunately, there are also several solutions available to overcome them. Wastewater ...
Cause of the Disease Infectious pancreatic necrosis (also known as Acute catarrhal enteritis) is one of the first described and most extensively studied diseases of fish. There are strains and substrains of IPN virus that can be differentiated by serological, biochemical and genetic means. The VR-299 (type 1) strain was originally isolated in North America and has since been found almost ...
Beijing, China (CNN)A major breakthrough in 3-D printed medicine could bring hope to nearly 1.8 billion patients with cardiovascular disease. Chinese scientists working for Sichuan Revotek have successfully 3-D printed blood vessels and implanted them in rhesus monkeys, the company said. It is a major step on the road to mass printing human organs for transplants. The company ...
Nanobiotechnology refers to the ability to create and manipulate biological and bio-chemical materials, devices, and systems at atomic and molecular levels. Nano delivery systems hold great potential to overcome some of the obstacles in bio-pharmaceutical production, such as water soluble/insoluble pharmaceutical drugs and cosmetic ingredients, risks of toxicity, ...
Nanostructured hydroxyapatite (nHA) exhibits improved mechanical properties and biocompatibility. To optimise the benefits of nano-sized precursors, the particles must have a uniform shape and size and minimum degree of agglomeration. In this study nHA was synthesised using an Iranian strain of Serratia. The powder was synthesised in different pH of reaction solution and incubation temperatures. ...
Xenotransplantation is becoming an independent political and regulatory issue. Most national regulations and international recommendations prescribe a precautionary approach, including strict monitoring and surveillance of patients. This is due to the risk of xenosis, a disease induced by non-human biological material. The paper shows how the precautionary approach violates fundamental principles ...
At the same time, a number of risks associated with processing and storing of biological material and corresponding data have been diagnosed. This paper focuses on how institutionalised transnational networks of biobanks generate practical answers to some of these risks. Drawing upon three case studies – GenomEUtwin, EuroBioBank and P3G – we illustrate how soft ...