Bone Formation Articles & Analysis
12 articles found
Posterolateral Rabbit Spinal Fusion Study I. Introduction Autologous bone has long been the gold standard for bone graft substitute in spinal fusion procedures. The limited supply and morbidity associated with using autologous graft material led to the development of alternative bone grafting materials. Bioactive glass has a long history of biomedical use and has been shown to facilitate mineral ...
Increased expression of MMPs is detected at different stages of mammalian development, from embryonic implantation to morphogenesis of different tissues and organs, including lung, bone and blood vessels. MMPs are involved in vascular smooth muscle growth, proliferation, migration, and relaxation. ...
Introduction to OsteoporosisOsteoporosis is a systemic multi-causal skeletal disease that is prone to fractures due to changes in systemic bone mass and microstructure of bone tissue, resulting in increased bone fragility. ...
Fracture non-unions have lifelong consequences and a debilitating impact in patients' life. Bone-grafts, allografts and xenograft are currently used to treat bone fractures; however, they have limitations. To overcome these limitations, we herein present a synthetic bone graft substitute composed of PdlLGA and rhBMP-2. We have demonstrated the ...
In calcium phosphate ceramics, hydroxyapatite (HAP) can form chemical bonding with cartilage tissue due to its molecular structure and calcium-phosphorus ratio, which are very similar to the inorganic components of normal bone and have excellent biological activity and osteoinductivity. In the implantation of bone defect, there is no fibrous tissue interface ...
ByMatexcel
ABL = abaloparatide; ALN = alendronate; vBMD = volumetric bone mineral density; DXA = dual-energy X-ray absorptiometry; PBO = placebo. 3.3 Bone structural parameters The ABL/ALN group showed greater improvements in bone structural parameters that are considered relevant to bone strength. ...
This dual approach was observed to provide higher level of vascularization and new bone formation in vivo. While applied in this case for bone regeneration, this technique could be easily adapted to prevascularise scaffolds to target regeneration of any tissue and organs. ...
ByRegenhu
Mesenchymal stem cells (MSC) differentiate towards multiple lineages that participate in bone formation and are often utilized for bone regeneration therapy. ...
Osteogenesis, or new bone formation, begins in the early stages of embryonic development and continues postnatally until skeletal maturity is reached in early adulthood. Osteogenesis reoccurs in the event of bone trauma, such as a fracture or surgically created defect. Bone mass can also increase in response to chronic weight ...
PEEK is biocompatible, similar in elasticity to bone, and radiolucent; however, it has been shown to be inert and does not integrate well with bone. Recent efforts have focused on increasing the bioactivity of PEEK by modifying the surface to improve the bone-implant interface. We have employed a novel Accelerated Neutral Atom Beam technique ...
Leptin plays a role in foetal growth. Osteocalcin, a bone specific protein, reflects bone formation rate. This study aims to investigate the effect of leptin and osteocalcin on physical growth of newborns. ...
Wnt/β-catenin signaling also plays a critical role in bone formation. Single Krm mutants show normal bone formation and bone mass, while double mutants show increased bone volume and bone formation parameters. ...