Cancer Specific Articles & Analysis: Older
22 articles found
Breast cancer remains one of the most prevalent malignancies affecting women worldwide, necessitating innovative approaches for effective treatment and research. ...
By introducing a functional gene into the cells with these symptoms, researchers hope to correct the inherited gene mutation and potentially cure the disease. Gene delivery in cancer treatment involves the use of viral or non-viral vectors to deliver therapeutic genes into cancer cells. These approaches allow the targeted delivery of genes that can inhibit ...
This analysis is mainly based on the following aspects:1. Ensure Specificity and TargetingThe main advantage of ADC lies in its high specificity for specific cancer cell surface antigens. ...
The antibody component specifically targets surface antigens on specific cancer cells, while the drug component is responsible for killing these bound cancer cells. ...
Immunohistochemistry is the study of the localization, characterization, and relative quantification of peptides and proteins in tissue cells using the antigen-antibody reaction, in which an antigen specifically binds to an antibody and a chemical reaction results in the visualization of dyes such as fluorescein and other chromogens, as well as enzymes, metal ions and isotopes, ...
For instance, engineered antibodies are being developed to target specific cancer cells with high precision, while engineered enzymes are being designed to break down harmful molecules in the body. Biotechnology and Industrial Applications: Protein engineering is playing an increasingly important role in industrial biotechnology, enabling the production of ...
In general, the incidence of ADA of ADCs is less in patients targeting hematologic cancer than in patients targeting solid cancer; Most ADA is specific to the monoclonal antibody domain of the ADC. ...
Microarray Analysis in Methylation Detection A number of hypomethylation intervals (hypomethylated blocks) are prevalent in multiple cancers. Ninety-five percent of the DNA methylation changes in cancer occur in those regions. ...
Rolled out as part of the Biden-Harris Administration’s Cancer Moonshot, the goal of EOM is to improve the experience of cancer patients, while advancing health equity and increasing access to care, as well as reducing Medicare spending. ...
Professor Fu Haian's team at Emory University published a paper entitled: “Systematic discovery of mutation-directed neo-protein-protein interactions in cancer” online in Cell. In this study, they mapped the first draft neo-protein-protein interaction (neoPPI) network specific for common cancer gene mutations and found that the ...
The Barbara Ann Karmanos Cancer Center, located in midtown Detroit, is the only National Cancer Institute (NCI)-designated comprehensive cancer center in metro Detroit and one of just 51 centers of its kind in the United States. ...
The researchers expose us to a radically different way of thinking in this article: instead of working on T cells, they focus on changing cancer cell antigens. They employed antibodies to deliver viral antigens to the tumor location and trigger virus-specific T lymphocytes to target cancer cells, destroying them. The corresponding author of ...
In the study, the researchers propose a new method that mainly involves extensive screening of monoclonal antibodies against primary human tumor samples with the aim of identifying cancer-specific conformational epitopes throughout the protein that cannot be identified by transcriptome or proteome analysis. ...
In honor of World Cancer Day, we sat down with two Adapters to understand how their personal experiences with cancer intersect with their work at Adaptive. ...
To date, CAR-T cell therapies have necessitated the collection of a patient's own T cells, which are then genetically reprogrammed in the laboratory to recognize specific cancer cells, allowing them to identify and destroy cancer cells once they are reintroduced into the body. ...
About Treos Bio Limited Treos Bio uses computational data science and proprietary biomarkers to develop precision off-the-shelf and personalized peptide-based cancer immunotherapies. The Company has developed a unique ability to match the antigens expressed by a specific cancer to the individual patient’s target recognition mechanism ...
The blood test was found to detect colorectal cancer with 92 percent sensitivity and 97 percent specificity. It also was shown to have 89 percent sensitivity and 97 percent specificity detecting early-stage cancer. ...
The coronavirus pandemic remains one of the top concerns within the United States. However, Johns Hopkins, and other research centers, are actively working to continue medical research in all divisions of medicine and health. Learn the ongoing studies at Johns Hopkins, what issues they are solving and how we can all make a difference. ...
Gabrielle is researching novel α-helical peptide inhibitors of breast cancer oncogene LMO4. She has been working to redesign the peptide protein interface of LMO4 by replacing the traditional β-strand binding partners with novel inhibitory α-helical ones and designing a high throughput screening mechanism to identify these peptides. ...
Cancer survival rates decrease with age, in part because the efficacy of cancer therapies declines in older individuals. Chemotherapy and radiotherapy wreak havoc on the immune system, kill both healthy and cancerous cells alike and cause a buildup of cellular waste in the tissue. ...