Cancer Specific Articles & Analysis
28 articles found
Human ovarian epithelial cells play a crucial role in ovarian function and have become a significant focus in cancer research, specifically ovarian cancer. The ability to study these cells in a laboratory setting has been greatly enhanced through the development of immortalized human ovarian epithelial cell lines, particularly those that utilize ...
Alfa Cytology has revealed new FAP-targeted therapeutics development services that aim to develop precise and effective cancer treatments. Alfa Cytology has introduced its groundbreaking initiative which targets fibroblast activation protein(FAP) for cancer therapies. ...
In recent years, the field of antibody drug design has become increasingly significant in the realm of therapeutic development, driven by the need for more effective and targeted treatments for various diseases, including cancer, autoimmune disorders, and infectious diseases. Antibodies, which are proteins produced by the immune system, have the ability to ...
This specificity is achieved by linking a radioactive isotope to a monoclonal antibody or small molecule that targets specific cancer antigens. ...
Antibody-Drug Conjugates (ADCs) represent a groundbreaking advancement in targeted cancer therapy, combining the specificity of antibodies with the potency of cytotoxic drugs. ...
Unlike conventional treatments that target both healthy and cancerous cells, immunotherapy empowers the body's immune system to recognize and combat cancer cells more selectively and effectively. ...
Breast cancer remains one of the most prevalent malignancies affecting women worldwide, necessitating innovative approaches for effective treatment and research. ...
By introducing a functional gene into the cells with these symptoms, researchers hope to correct the inherited gene mutation and potentially cure the disease. Gene delivery in cancer treatment involves the use of viral or non-viral vectors to deliver therapeutic genes into cancer cells. These approaches allow the targeted delivery of genes that can inhibit ...
This analysis is mainly based on the following aspects:1. Ensure Specificity and TargetingThe main advantage of ADC lies in its high specificity for specific cancer cell surface antigens. ...
The antibody component specifically targets surface antigens on specific cancer cells, while the drug component is responsible for killing these bound cancer cells. ...
Immunohistochemistry is the study of the localization, characterization, and relative quantification of peptides and proteins in tissue cells using the antigen-antibody reaction, in which an antigen specifically binds to an antibody and a chemical reaction results in the visualization of dyes such as fluorescein and other chromogens, as well as enzymes, metal ions and isotopes, ...
For instance, engineered antibodies are being developed to target specific cancer cells with high precision, while engineered enzymes are being designed to break down harmful molecules in the body. Biotechnology and Industrial Applications: Protein engineering is playing an increasingly important role in industrial biotechnology, enabling the production of ...
In general, the incidence of ADA of ADCs is less in patients targeting hematologic cancer than in patients targeting solid cancer; Most ADA is specific to the monoclonal antibody domain of the ADC. ...
Microarray Analysis in Methylation Detection A number of hypomethylation intervals (hypomethylated blocks) are prevalent in multiple cancers. Ninety-five percent of the DNA methylation changes in cancer occur in those regions. ...
Rolled out as part of the Biden-Harris Administration’s Cancer Moonshot, the goal of EOM is to improve the experience of cancer patients, while advancing health equity and increasing access to care, as well as reducing Medicare spending. ...
Professor Fu Haian's team at Emory University published a paper entitled: “Systematic discovery of mutation-directed neo-protein-protein interactions in cancer” online in Cell. In this study, they mapped the first draft neo-protein-protein interaction (neoPPI) network specific for common cancer gene mutations and found that the ...
The Barbara Ann Karmanos Cancer Center, located in midtown Detroit, is the only National Cancer Institute (NCI)-designated comprehensive cancer center in metro Detroit and one of just 51 centers of its kind in the United States. ...
The researchers expose us to a radically different way of thinking in this article: instead of working on T cells, they focus on changing cancer cell antigens. They employed antibodies to deliver viral antigens to the tumor location and trigger virus-specific T lymphocytes to target cancer cells, destroying them. The corresponding author of ...
In the study, the researchers propose a new method that mainly involves extensive screening of monoclonal antibodies against primary human tumor samples with the aim of identifying cancer-specific conformational epitopes throughout the protein that cannot be identified by transcriptome or proteome analysis. ...
In honor of World Cancer Day, we sat down with two Adapters to understand how their personal experiences with cancer intersect with their work at Adaptive. ...