cartilage Articles
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L-sox5 and sox6 drive expression of the aggrecan gene in cartilage by securing binding of sox9 to a far-upstream enhancer
The Sry-related high-mobility-group box transcription factor Sox9 recruits the redundant L-Sox5 and Sox6 proteins to effect chondrogenesis, but the mode of action of the trio remains unclear. We identify here a highly conserved 359-bp sequence 10 kb upstream of the Agc1 gene for aggrecan, a most essential cartilage proteoglycan and key marker of chondrocyte differentiation. This sequence directs ...
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Discover Our Unique Cartilage Repair Solution
There are now nearly 230 million patients with osteoarthritis in the world and 4 million additional cartilage lesions per year. Osteoarthritis results anatomically in the destruction of cartilage in the joints (knee, hip, etc.), which causes severe pain and a significant reduction in mobility. ACS Biotech is an innovative biotechnology company created in 2013 by Pascale Hazot, Doctor of ...
By ACS Biotech
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Fabrication Of In-Vitro Phenotypically Stable Engineered Articular Cartilage
Researchers from IRCCS Istituto Ortopedico Rizzoli and Indian Institute of Technology, Delhi (IIT) used their REGENHU bioprinters to fabricate an in vitro phenotypically stable engineered articular cartilage by embedding human bone marrow-derived stromal cells (hMSCs) in a cell-laden silk fibroin–gelatin (SF-G) bioink. The bioprinted constructs allowed the in vitro study of chondrogenic ...
By Regenhu
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Buy PPE Mask Wholesale Online USA
HY Supplies offers disposable surgical face masks wholesale in the USA, Canada, and Mexico region. Order now and get the best mask at an affordable price among the competitors. Product Description: The non-woven outer layer, Melt-blown filter layer and Anti-bacterial inner layer. 50 Pieces/Box & 40 Boxes/ Case ->2000 Pieces / Case Pack Certifications: BFE 95% (Bacterial ...
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Corporate recycling, sunny side-up
Food manufacturing and packaging go hand in hand. What may not be so obvious, however, is that the links between the two are about to become a lot more, er, ineggstricable. That’s right, thanks to some pioneering work out of England, we’ve learned that eggs themselves may contain the answers to some of the world’s environmental woes. Scientists out of the University of ...
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A New Concept of Mosaicplasty: Autologous Osteoperiosteal Cylinder Graft Covered With Cellularized Scaffold
Abstract: A concern regarding osteochondral autograft transfer for chondral defects is donor-site morbidity of the knee, the most common source of the autograft. To avoid the drawbacks of osteochondral autograft transfer, a cylindrical osteoperiosteal graft harvested from the iliac crest covered by a same-sized cylinder of hyaluronic acidebased polymer scaffold pretreated with bone marrow ...
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Meniscus Cutter
Description Application domain: for arthroscopy endoscope Material: Super-high rust-resistant high-hardness stainless steel, ceramics, generally stainless steel LZQ is an OEM factory for all kinds of shaver blades, such as Endoscopic/Arthroscopic Shaver blade P259, Bone Drill Point P227, Bone Fetcher P165, Drill Bit 096, etc. We use the material of stainless steel and ceramic. Meniscus ...
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The Innovative Cartilage Repair Solution, A Participatory Project!
ACS Biotech has chosen the participatory economy to reaffirm its values and allow investors to give meaning to their savings while financing the real economy on a major public health ...
By ACS Biotech
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What Is Collagen?
Collagen is a family of proteins. At least 30 kinds of genes encoding collagen chains have been found, which can form more than 16 kinds of collagen molecules. According to its structure, it can be divided into fibrous collagen, basement membrane collagen, microfibrillar collagen, anchored collagen, hexagonal reticular collagen, non-fibrous collagen, transmembrane collagen, etc. According to ...
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Saw Blade
A metallic running instrument having an side of sharp, tooth like projections, for dividing bone, cartilage, or plaster; edges may additionally be attached to a inflexible band, a flexible wire or chain, or a motorized oscillator. Orthopedics A hand-held electric saw with an oscillating blade, used to cutthe cranium, ribs andother bones. A sternal noticed is a dental saw blade used to perform ...
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SPACE BIO-3D PRINTING FROM HUMAN CARTILAGE TO THYROID GLAND IN RODENTS AND TO SPACE ARTIFICIAL MEAT
Space bio-3D printing from Human Cartilage to Thyroid Gland in Rodents and to Space Artificial Meat: SUNKYE Satisfies the Connection and Signal System of Bio-3D Printing in Micro-gravity Environment Space bio-3D printing may be a concept we've heard recently. But as with 3D printing technology, there was only a short accumulation before it happened! Do we need Space bio-3D printing? Can't we ...
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How Much Do You Know about Glycosaminoglycans?
Glycosaminoglycan (GAG) is a general term for the glycan part of proteoglycan macromolecules. Glycosaminoglycans are large linear polysaccharides composed of repeating disaccharide units, and their main configuration contains amino sugars and uronic acids (glucuronic acid and/or iduronic acid). Glycosaminoglycans can be divided into chondroitin sulfate, dermatan sulfate, keratan sulfate, ...
By CD BioGlyco.
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Uses of Recombinant Human Collagen
Collagen is the main structural protein in vertebrates. It plays an essential role in providing a scaffold for cellular support and thereby affecting cell attachment, migration, proliferation, differentiation, and survival. Natural animal collagen and its recombinant collagen are favorable replacements in human tissue engineering due to their remarkable biomedical property. However, this ...
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Surgical Site Infection: Methods of Prevention & Tools for Predicting Risk - Case Study
Medical History A 55-year-old white male has degenerative arthritis of the knees. 10 months ago, the patient underwent total knee replacement on the left knee without complication. The surgical incisions had closed without signs of surgical site infection. At the time, he made a good recovery. He is fully functional and fully independent. Patient is a chain smoker with a wife and two children. He ...
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Bioinspired Hydrogel To Improve The 3d Printability Of Mechanically Demanding Tissues Such As Intervertebral Disc
Researchers from Albert-Ludwigs-Universität Freiburg im Breisgau, Université Claude Bernard Lyon 1, Universidad Central “Marta Abreu” de Las Villas and Johannes Gutenberg-Universität Mainz developed a 3d printable, bioinspired hydrogel composed of two different biopolymers, chitosan and cellulose nanofibers, through an environmentally friendly process by avoiding both ...
By Regenhu
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Unveiling The Manifold Potentials: Mesenchymal Stem Cells & Bone Marrow Mesenchymal Stem Cells
In the vibrant realm of cellular biology and regenerative medicine, mesenchymal stem cells (MSCs) hold unparalleled potential for therapeutic applications. Particularly noteworthy are bone marrow mesenchymal stem cells (BM-MSCs), a subtype of MSCs. Their unique properties make them indispensable resources for developing ground-breaking solutions for various medical conditions. Mesenchymal stem ...
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Introducing CellQART Cell Culture Inserts: Giving New Life to Tissue Engineering
The new line of cellQART cell culture inserts, offered by Sterlitech, have important applications in medical science. Cell culture inserts have been used widely in tissue engineering because they allow access to both sides of the membrane. Each insert is designed to fit inside the well of a culture plate, making it more effective for growing 3D tissue layers than seeding cells directly on the ...
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Pioneering VeraForm in Head and Neck Cancer Treatment: Sarcomatoid Carcinoma Tumor Bed Marking
Head and neck cancer surgery presents a number of unique challenges, not only for the surgeon but for the radiation oncologist who will subsequently treat those patients. Great care with an emphasis on precision must be taken to ensure that critical structures and tissues avoid collateral damage when possible. However, given the surgical site often lies in soft tissue, exact identification of the ...
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Do You Really Know Hydroxyapatite?
As an important branch of biomedical materials, bioceramics are mainly used to manufacture hard tissue repair devices and artificial organs in vivo, and generally have good biocompatibility. According to the chemical activity in the physiological environment, bioceramics can be divided into three types: Nearly inert bioceramics, only weak or no chemical reaction occurs when exposed to the ...
By Matexcel
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What are Surgical Options for ACL Tears?
The anterior cruciate ligament, better known as the ACL, is one of the two ligaments in the center of your knee that connect the femur to the tibia. It’s also one of the most commonly injured, especially among athletes. Unlike many other ligaments in the body, the ACL does not have the ability to heal on its own. A thick liquid – called synovial fluid – reduces friction ...
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