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Cartilage Articles & Analysis
31 articles found
Bone Biology and Chondrogenesis Although MGP is an inhibitor of ectopic calcification, it also plays a nuanced role in skeletal development. In cartilage, MGP modulates chondrocyte maturation and endochondral ossification. ...
Adhesive-backed nasal strips are worn externally over the nose bridge to widen the nostrils for better breathing. These are available over-the-counter aids designed to improve airflow, nasal congestion and reduce ...
Clinical trials have demonstrated the efficacy of hMSCs in promoting cartilage regeneration and improving heart function after myocardial infarction. ...
These cells possess the remarkable ability to differentiate into a variety of cell types, including cartilage, bone, and fat cells, making them invaluable for therapeutic applications. ...
In-vivo test results have histologically demonstrated the presence of all 5 bone-forming elements (Chondrocytes, Osteocytes, Bone Marrow Cells, Cartilage, and New Bone). ACTIGEN™ Verified Inductive Bone Matrix has also been in-vitro lot tested for the endogenous BMP-2 test marker for osteoinductivity. ...
Uses of Recombinant Human Collagen Due to its good biocompatibility, low immunogenicity, stabilized property, recombinant human collagen has been widely used in tissue engineering (such as vascular scaffolds engineering, cartilage, bone defect repair), skin injury treatment, drug delivery, etc. [1]. ...
Mesenchymal stem cells are multi-potent stromal cells capable of differentiating into various cell types like osteoblasts (bone cells), chondrocytes (cartilage cells), and adipocytes (fat cells). They were initially identified in the bone marrow, but have since been found in various other tissues including adipose tissue, peripheral blood, cord blood, fallopian tube, and fetal ...
Clinical Applications of MMP-3 MMP-3 and Rheumatoid Arthritis (RA) Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by synovial cell proliferation and infiltration of lymphocytes, leading to destruction of joint cartilage and bone erosion. Previous studies have shown that MMP-3 levels in the serum of RA patients are significantly higher compared ...
As part of our quick fire questions series – or QFQs – we spoke to Dr. Andy Franklyn-Miller, Chief Medical and Innovation Officer at Nuritas about intelligent ingredients, explaining peptides and proving an AI model in life science. There is a lack of innovation within ingredients in food, many have been discovered decades ago, mostly with cost, taste and texture in mind. However as ...
Nuritas has recently published the results of two clinical studies on their next-generation ingredient PeptiStong™. Identified within fava beans, with self-affirmed GRAS and Health Canada approval, Peptistrong™ contains cell-signalling peptides which, when compared against milk proteins, were found to improve the rate of muscle protein synthesis during recovery. In this New Protein ...
Polylactic acid materials are expected to be used in the repair and cultivation of blood vessels, ligaments, skin, liver and other tissues. 2.2 Polyanhydride can be used for tissue repair The water-soluble protein such as cartilage protein, bone protein and polyanhydride carriers were implanted into the wound site of the bone tissue. ...
Patient had suffered from non-inflammatory degenerative arthritis for years, and his physician noticed frayed and irregular cartilage in his knees about two months before his right knee arthroscopy as noted from an MRI. Several years ago, the patient had also suffered an ACL and meniscus tear as a result of playing pick-up basketball at the gym. The torn ligament and ...
If left untreated, instability can cause damage to the nearby meniscus and articular cartilage, and osteoarthritis man develop over time. You should consult with your doctor to determine if surgery is recommended and if so, which approach is best for you. ...
It is particularly of use for lesions that present with large subchondral cysts in computed tomography scans (Fig 1 A-C) and degeneration of the overlying cartilage in MRI (Fig 2 A-C). Surgical Technique The surgical video is shown in Video 1. ...
Ror2 correlates with the early formation of the chondrocytes and cartilage, and it was highly expressed in the limb15. Pathway analysis revealed that cluster 1 was associated with erythrocyte differentiation, cluster 5 corresponded to forebrain development and cluster 6 was involved in limb development, consistent with anatomical annotations (Supplementary Fig. 3). ...
As far as hyaluronic acid is concerned, in humans we find it present in the umbilical cord, connective tissue, synovial fluid, cartilage, blood vessels, and vitreous fluid (gelatinous material found between the lens and the retina of the eye); while in nature, it is only present in mollusks. Another difference is that chondroitin sulfate in the body is present in skeletal ...
In calcium phosphate ceramics, hydroxyapatite (HAP) can form chemical bonding with cartilage tissue due to its molecular structure and calcium-phosphorus ratio, which are very similar to the inorganic components of normal bone and have excellent biological activity and osteoinductivity. ...
ByMatexcel
Finally, there are joints and cartilage, which consist of cellular building blocks (chondrocytes) that generate an extracellular matrix composed of collagen and proteoglycans (mainly aggrecan). Collagen fibers make up 70% of cartilage and are responsible for the structure and strength of cartilage, while proteoglycans are the lubricants of ...
This work allows expanding the library of the so far used biopolymer compositions for 3D printing of mechanically performant hydrogel constructs, purely based in the natural polymers chitosan and cellulose, offering new perspectives in the engineering of mechanically demanding hydrogel tissues like intervertebral disc (IVD), cartilage, meniscus, among ...
ByRegenhu
This was achieved by means of a thorough proteomic analysis and evaluation of the protein expression related to cartilage-specific signaling pathways. This knowledge could provide essential insights in understanding how the bioprinted construct can create an active and instructive microenvironment for cells to promote cartilage-specific tissue regeneration. ...
ByRegenhu