Clinical And Research Articles & Analysis: Older
236 articles found
The availability of premade AAV particles allows for a more accessible approach to gene therapy research. Researchers can focus on experimental design and therapeutic development rather than spending substantial time generating viral vectors. ...
Alfa Cytology, celebrated for its cutting-edge biotech solutions and extensive tumor research expertise, has recently introduced brain tumor drug development services, designed to empower researchers in understanding the intricacies and unique challenges associated with brain tumors. ...
If you’re one of the 45% of American adults who snores at least on an occasional basis, you may get teased about it. Snoring is no joke at all and may a warning sign of an even more serious underlying condition, or sleep apnea. If you’re a sleep apnea victim, your breathing can be interrupted for short periods of time while you sleep. Additionally, not just the snoring individual ...
The prime concern resides in assessing the clinical efficacy of these therapies, as their long-term impact is yet to be conclusively quantified. ...
In fact, cell therapy manufacturers need to take steps to ensure that reagents used for further manufacturing are removed before the cells are used in the clinic. Transition Program for GMP Cytokines - For each cytokine, Creative Bioarray provides a certificate of analysis, stability data, and bioactivity documentation for comparison to research-grade ...
Medical advancement relies on clinical trials, which are essential for the development of safe and effective innovative treatments. However, the success and general applicability of these treatments heavily depend on the diversity of the participants involved¹?³. This blog explores the importance of achieving data diversity in clinical trials to enhance clinical trial results and ...
Therefore, the detection of sialic acid proteins holds significant value in disease diagnosis, biomedical research and drug development.Biological Importance of Sialic Acid ProteinsSialic acid proteins play an indispensable role in many physiological and pathological processes. ...
Discover how matched tumor-normal sequencing can help clinical researchers detect the somatic origin of variants with certainty. ...
Here are some specific examples to illustrate the selection of the number of parallel samples in different situations.Basic Biological ResearchIn basic epigenomics research, such as studying how the methylation status of a gene affects gene expression, at least three parallel samples are usually needed. This can help researchers distinguish between biological ...
These inhibitors aim to prevent tissue damage by blocking elastase's proteolytic actions. Pharmaceutical research is focusing on designing synthetic inhibitors, as well as exploring natural compounds with elastase-inhibitory properties. ...
In response to the emerging needs in global healthcare, SOPHiA GENETICS has just revealed the New Generation SOPHiA DDM™ Platform, aiming to stay at the forefront of precision medicine and address today the healthcare needs of tomorrow. ...
Antibody-drug conjugates (ADCs) represent a groundbreaking class of therapeutics that combine the specificity of monoclonal antibodies (mAbs) with the potent cytotoxic effects of small-molecule drugs. This synergistic approach allows for targeted delivery of the cytotoxic agent to cancer cells while sparing healthy tissues, thereby reducing side effects and enhancing therapeutic efficacy. ADC ...
ESMO updated its recommendations for NGS in advanced cancers this year, urging broader use of NGS in additional cancer types and the inclusion of tumor-agnostic biomarkers. The ESMO Precision Medicine Working Group (PMWG) first published its recommendations for when to use next-generation sequencing (NGS) in routine practice for patients with metastatic cancers in 20201. At that time, based ...
Typically, an amplification gradient of 10 to 50 times is used for small-scale production, aiding in process investigation and research. CD Formulation has a production setup that can scale up gradients by 10 to 30 times. This system, equipped with flexible and high applicability supporting facilities, can handle both research and small-scale production, ...
Meanwhile, cancer vaccines stand out in research for their safety, effectiveness, and low cost. With professional knowledge of PC (particularly intra-tumor heterogeneity, TME crosstalk, and micro-environmental instability) and powerful cross-platform collaboration capability, Alfa Cytology has launched a series of PC vaccine development services to meet ...
DIA technology has a wide range of applications in biomedical research, disease biomarker discovery, and drug development.DIA Proteomics SequencingDIA technology systematically scans the entire mass range during mass spectrometry analysis, rather than analyzing only a few preselected ions. ...
Understanding Sleep Apnea and Its Types Sleep apnea is a sleep-related breathing disorder that results in poor sleep quality and can lead to daytime fatigue or sleepiness, forgetfulness, and irritability. According to the Mayo Clinic, there are 3 types of sleep apnea to be aware of as follows: OSA or obstructive sleep apnea is the more common form of the disorder and affects ...
In addition, many CDM systems are not user-friendly or interactive, making it difficult for users to get the most out of them. What challenges do clinical data management systems currently face? Clinical Trial Complexity The modern clinical trial design requires real-time data modelling and simulation to provide reliable information that ...
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Ongoing research and inventions in the field of oncology focus on the development of small molecule drug therapies for use in brain tumor resection. ...
Development and approval of nOPV2 The ambitious effort to develop the nOPV2 vaccine required years of research, clinical trials, and strategic partnerships. By utilizing advanced genetic techniques, scientists were able to develop a vaccine with improved genetic stability. ...