Clinical Assessment Articles & Analysis: Older
17 articles found
However, the execution of cell and gene therapies is veiled in complexities. The prime concern resides in assessing the clinical efficacy of these therapies, as their long-term impact is yet to be conclusively quantified. Hence, an extensive lattice of regulations envelops these modalities, mandating rigorous preclinical studies and clinical ...
Discover how matched tumor-normal sequencing can help clinical researchers detect the somatic origin of variants with certainty. In the era of precision oncology, it has become increasingly common for patients diagnosed with cancer to undergo tumor sequencing. Identifying the mutations that make up a tumor’s genomic landscape can help guide selection of targeted therapies and inform ...
In England, approval from the National Institute of Health and Care Excellence (NICE) demonstrates that a device or medicine has been assessed by independent committees and has made evidence-based recommendations for the health and social care sector1. Technology appraisals2 assess the clinical and cost-effectiveness of health technology, ...
However, the execution of cell and gene therapies is veiled in complexities. The prime concern resides in assessing the clinical efficacy of these therapies, as their long-term impact is yet to be conclusively quantified. Hence, an extensive lattice of regulations envelops these modalities, mandating rigorous preclinical studies and clinical ...
Heart failure with preserved ejection fraction (HFpEF) is a clinical syndrome in which patients have signs and symptoms of HF as the result of high left ventricular (LV) filling pressure, despite normal or near-normal LV ejection fraction (EF). ...
A report on the use of the Doraya catheter in 2 patients demonstrated an increase in urine output in patients with initial poor diuretic response following placement of the catheter.69 A first in man clinical study is currently ongoing to assess feasibility, safety, and hemodynamic effects in patients with ADHF.70 Selective (S) Direct intrarenal delivery of ...
With the rising demand for improving patient safety in clinical trials, the adoption of patient-centric solutions is considered the best route to enhance data accuracy and experience automated workflows. ...
ByClinion
Methods We did a pilot study at three hospitals in Shanghai to assess the accuracy of pulse oximetry plus clinical assessment for detection of congenital heart disease. ...
HYPOTHESIS: The aim of this study was to determine the diagnostic yield of a patient-triggered CER combined with continuous automatic arrhythmia detection in the evaluation of sporadic dizziness/syncope or palpitations and its clinical relevance in assessing the further management. METHODS: We investigated 101 consecutive outpatients (54 +/- 20 years, 40 ...
ByNovacor
When promising drug candidates are identified for further investigation in clinical trials, sponsor companies are usually optimistic about outcomes. ...
Imagine you’ve just been diagnosed with cancer and you’re enrolled in a clinical trial for a promising new drug. You notice that after chemotherapy you struggle with occasional fatigue. ...
ByAiCure
The DASCOR Disc Arthroplasty Device seemed to perform well clinically but was discontinued in 2009. While there are no commercially available NRDs today, the potential advantages of using such devices have prompted a renewed interest in further developing the technology and assessing long-term outcomes for the DASCOR device. Methods A retrospective review of ...
As a relatively new concept, Patient—Centered Outcome Measures (PCOM) aims to place patients, their families and carers at the heart of the decision making that concerns their health, rather than leave these assessments solely to the clinician. Although PCOM and quality of life measures are often used for people with neurogenic bladder and bowel dysfunction, few ...
We continue to assess the outcomes of T-Pin cases in the orthopaedic surgery community. We are seeking qualified surgeons to collect outcome data for patients whose fractures have been treated with the T-Pin System. Subjetive and objective assessment of factors such as patient selection factors, intraoperative observations and clinical pearls, ...
Participants completed 5 and 10 repetitions of each activity on 2 separate sessions (time 1 and time 2) and completed clinical assessments (Fugl-Meyer Upper Extremity Assessment and Action Research Arm Test). Mean reach-to-grasp counts (ie, hand counts) were compared across activities. Scaling properties were assessed by the ...
To this end, a dynamic discrete event simulation model of a clinic operation is developed to assess current clinic performance under various no–show rates and patterns and test several overbooking strategies to improve clinic's efficiency and enhance performance. ...
To this end, a dynamic discrete event simulation model of a clinic operation is developed to assess current clinic performance under various no-show rates and patterns and test several overbooking strategies to improve clinic's efficiency and enhance performance. ...