Clinical Performance Articles & Analysis
44 articles found
Medical advancement relies on clinical trials, which are essential for the development of safe and effective innovative treatments. However, the success and general applicability of these treatments heavily depend on the diversity of the participants involved¹?³. This blog explores the importance of achieving data diversity in clinical trials to enhance clinical trial results and ...
POCT (Point-of-Care Testing) refers to clinical and bedside testing conducted in close proximity to patients. It is often not performed by clinical laboratory personnel. POCT holds significant importance in disease prevention, etiology determination, prognosis, enhancing treatment outcomes, and reducing healthcare expenses. It meets ...
People living with frontotemporal dementia, or FTD, are commonly misdiagnosed with psychiatric disorders or Alzheimer’s disease and other causes of dementia, such as Parkinson’s disease and vascular dementia. While frontotemporal dementia and Alzheimer’s disease can both cause dementia, there are distinct differences in impacted regions of the brain and, consequently, ...
At the turn of the last century, researchers ran clinical trials and validation studies on drugs that were already being used. ...
From clinical trial enrollment through completion, understanding medication adherence is critical to data integrity and AiCure offers a competitive edge where traditional methods fall short. ...
ByAiCure
Nanostics’ biomarker and machine learning-powered test, ClarityDX Prostate®, received a CE-IVD Mark. A CE-IVD Mark is required for all in vitro diagnostic (IVD) devices to be placed in the European Economic Area, Iceland, Norway, and Liechtenstein and allows Nanostics to market and sell ClarityDX Prostate® in these countries. The ClarityDX Prostate® test provides patients ...
Real-world data shows that at a 94% sensitivity level for prostate cancer ClarityDX Prostate® is 147% more specific than the PSA test for predicting clinically significant prostate cancer. Using ClarityDX Prostate® as a reflex test vs. PSA test alone could have resulted in 37% fewer unnecessary biopsies. The clinical study recruited men from two sites in Alberta, Canada, and one site ...
Clinical study launched in June 2022 with patient recruitment in Alberta with plans to expand to further sites across North America. The aim of the study is to validate a novel and minimally invasive liquid biopsy test for bladder cancer diagnosis using Nanostics’ ClarityDX® diagnostic platform. The study is supported in part by the Alberta Innovates AICE-Concepts Program with a ...
Meditation is often thought of as an avenue to clarity and self-awareness, but it may also be an avenue to better brain health. Emerging research suggests meditation may have significant benefits to brain health, ranging from improved mental and behavioral health to enhanced cognitive function. In this article, we will break down how meditation helps the brain and provide helpful tips for ...
Many neurological diseases, including Alzheimer’s disease, can be thought of as continuums, whether the presence and manifestation of the disease are different depending on the stage of the disease. In this article, we provide a high-level overview of the stages in the Alzheimer's disease continuum, with a focus on preclinical Alzheimer’s disease and its importance in patient care and ...
Linear Health Sciences was featured in MassDevice focused on the GCMI/LHS Partnership Medical device accelerator the Global Center for Medical Innovation has issued its 1st grant to Linear Health Sciences, developer of the Orchid safety release valve designed to prevent dislodgment of IVs. The Oklahoma City-based company said it is developing safety release valves for a variety of medical ...
In addition to the pandemic, the digitization of healthcare is rapidly shifting clinical trials from analog to hybrid or fully decentralized clinical trials, catalyzing the development and implementation of digital health technologies to support clinical research. Digital endpoints not only support the decentralization of clinical trials but also provide a means to collect more sensitive, ...
Thalidomide and its derivatives for the treatment of multiple myeloma and other conditions have demonstrated the potential of protein degraders, while ARV-471, an estrogen receptor degrader based on the drug development of thalidomide, is targeted at the early stage of breast cancer has continued to show superior performance in clinical trials. Currently, ...
Alzheimer’s and Parkinson’s disease are both neurological diseases that cause progressive damage to the brain, resulting in a decline in neurocognitive function. While Parkinson’s disease is known for affecting movement and function and Alzheimer’s disease is known for affecting cognition, they are a bit more complex than that. Below, we provide an overview of ...
Parkinson’s disease is a progressive neurodegenerative disease that is most commonly known for affecting movement. It primarily impacts dopaminergic, or dopamine-producing, neurons in a specific area of the brain known as the substantia nigra. Typically, symptoms develop slowly over years and continue to worsen as the disease progresses. While the manifestation of symptoms tends to vary ...
It is no secret that glucose, a form of sugar, is the main source of energy for every cell in our bodies, including our brain cells. Because the brain is packed with neurons, it uses more energy than any other organ in the body. Our brains reward us for consuming sugar. Whether you are eating a delicious meal, sharing a kiss with someone you love, or enjoying a sugary treat, the mesolimbic ...
Primary care practitioners are often the first to address a patient’s or family’s concerns about memory loss or the possibility of dementia. Detecting cognitive decline as early as possible is fundamental to a patient’s ability to receive earlier access to treatments and therapies, and, consequently, more effective treatment and improved health outcomes. There are several ...
We evaluated SelectMDx clinical performance in a cohort of German men undergoing initial prostate biopsy.Methods:The study population consisted of 443 men sequentially enrolled men who underwent initial prostate biopsy between July 2009 and December 2014 due to suspected PCa. ...
By now, you are likely aware of many of the well-established risks associated with smoking cigarettes, such as cancer, asthma, chronic obstructive pulmonary disease (COPD), diabetes, cardiovascular disease, and stroke. But did you know that research has discovered a link between smoking and cognitive decline? This research emphasizes the importance of identifying and controlling modifiable risk ...
Humans are inherently social beings who thrive on making and maintaining social relationships. Connecting with and supporting one another forms deep bonds that make us feel seen, valued, and like we belong. These social interactions are not only important for our emotional well-being but also for our physical well-being-maybe even more so than originally thought. Loneliness, an increasingly ...