drug abuse Articles
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Extraction of abuse drugs in biological media
Extraction methods are determined by the nature of the matrix, the drug to be isolated and the availability of equipment, staff and economic resources. This review critically describes the main extraction techniques commonly known as 'Liquid-Liquid' (LLE), those using modified Infusorial Earth (IE), Solid Phase Extraction (SPE), Solid Phase Micro Extraction (SPME) and Supercritical Fluids ...
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America`s Painkiller Epidemic and What You Can Do
A new study conducted by the National Safety Council (NSC), along with Indiana’s attorney general has found that 80% of Indiana employers have been impacted by prescription drug misuse and abuse by employees. 80% is a substantial figure, causing some to refer to this trend as a painkiller epidemic. This figure is not unique to Indiana, the NSC notes that the results would likely be ...
By SafetyNow
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Plethysmography for the assessment of opioid-induced respiratory depression
Opioid-related addiction, overdose and death is a widespread public health crisis. A recent paper published in The Journal of Pharmacology and Experimental Therapeutics by Dr. Renata Marchette working within the National Institute on Drug Abuse Intramural Research Program provides a model example of the how plethysmography can be used to assess ventilatory behavior changes that occur with opioid ...
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Analysis of drugs of abuse and explosives using GC-MS to compare results when using helium and hydrogen
Background Researchers from Prof. Guido Verbeck’s group at the University of North Texas (UNT) carried out analysis of drugs of abuse (DOA) and explosives using an ion trap GC-MS to compare results when using helium and hydrogen carrier and buffer gas. As well as comparing the two gases, the group also assessed a number of ion volumes with different orifice diameters to look at their ...
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Analysis of Opioids Using Isotope Dilution with GCMS-TQ8030 GC/MS/MS
Development of methods for analysis of drugs of abuse has become a high priority for both forensic toxicology and law enforcement. The large numbers of individual drugs and new "designer drugs" has made method development for these compounds a significant undertaking. Gas chromatography mass spectrometry (GCMS) has been used extensively for analysis of drug residues and trace-level drugs in ...
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CBD: Perils, Promise and Development for Neuropathic Pain
Cannabidiol, or CBD, is one of several compounds extracted from the cannabis (marijuana) plant. In recent years, CBD has become enormously popular, and its market is believed to be hundreds of millions of dollars. Believers and users of CBD extoll its benefits for inflammation, muscle soreness, pain, anxiety and a whole host of other things, including cancer. It is, however, very understudied. ...
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Alcohol relapse is linked to immune protein?
Scientists at the Scripps Research Institute have found that the immune protein CSF1 may cause anxiety during alcohol withdrawal. Some nuclei have the corticotropin-releasing factor receptor 1 crhr1 gene, and the glutamate transporter slc17a7 gene, but the glutamate decarboxylase gene gad2 does not, suggesting that they mainly constitute an excitatory population in the medial prefrontal cortex. ...
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Philly Pharmacologists are Developing a Promising Pain-Relieving CBD Analog Drug
Scientists from Temple’s Lewis Katz School of Medicine and local biopharma company Neuropathix are testing their compound, KLS-13019, which is intended to target chemotherapy-induced pain in cancer patients. Sara Jane Ward, assistant professor of pharmacology at Temple University’s Lewis Katz School of Medicine, and Douglas Brenneman, chief pharmacologist at Neuropathix, discuss ...
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Make Mental Health a Priority
There are nearly one billion people worldwide who suffer from mental disorders. There is a stigma surrounding mental health making it difficult to speak up and seek help. Covid 19 has been a huge impact on people's mental health all around the world. Within the first year of Covid-19, there has been a 25% increase in anxiety and depression worldwide. Not being able to leave the house to ...
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Learning How Meditation Helps the Brain
Meditation is often thought of as an avenue to clarity and self-awareness, but it may also be an avenue to better brain health. Emerging research suggests meditation may have significant benefits to brain health, ranging from improved mental and behavioral health to enhanced cognitive function. In this article, we will break down how meditation helps the brain and provide helpful tips for ...
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Alberta Sees an Alarming Rise in Suicide Rates Following Harsh Oilpatch Layoffs
Following rising rates of layoffs in Alberta’s oil and gas industry in response to low oil prices, suicide rates in that province have increased by an alarming 30 percent this year. There were 327 suicides recorded between January and June 2015 and it is predicted that number could swell to 654 cases by year’s end. According to the Centre for Suicide Prevention, Alberta sees ...
By SafetyNow
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Take Control of your Health this Movember
You may have heard of Movember, the month when men grow their facial hair in solidarity with men’s health issues, like testicular and prostate cancer. The trend has taken hold across the world and even generated its own spinoffs, like “No-Shave November.” Movember started in Australia as a grassroots movement and began to become widespread in the early 2000s. Since then, ...
By Evidation
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How to treat Depression without medication: What the Science says
Is it possible to treat depression without medication or antidepressants? There is a simple answer to this question: Yes. Yes, it is. Most people don’t know that you can treat depression at home, medication-free. If they do, most people don’t know how. The fact is, you don’t need pills to reduce depressive symptoms or even to recover from depression. By making a few lifestyle ...
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