Genomic Profile Articles & Analysis
12 articles found
Abnormalities in the genome can lead to tumorigenicity or other adverse effects, making regular genomic assessment a vital part of iPSC characterization. Epigenetic Profiling The epigenetic landscape of iPSCs also plays a significant role in their characterization. ...
Clinical trials are the backbone of modern medicine, responsible for bringing innovative, safe, and efficient treatments to market after rigorous testing and evaluation. However, the conventional process of conducting these trials has often been long, expensive, and fraught with inefficiencies¹. The advent of predictive analytics is reshaping the landscape of clinical trials, ushering in a ...
Discover how matched tumor-normal sequencing can help clinical researchers detect the somatic origin of variants with certainty. In the era of precision oncology, it has become increasingly common for patients diagnosed with cancer to undergo tumor sequencing. Identifying the mutations that make up a tumor’s genomic landscape can help guide selection of targeted therapies and inform ...
Medical advancement relies on clinical trials, which are essential for the development of safe and effective innovative treatments. However, the success and general applicability of these treatments heavily depend on the diversity of the participants involved¹?³. This blog explores the importance of achieving data diversity in clinical trials to enhance clinical trial results and ...
In response to the emerging needs in global healthcare, SOPHiA GENETICS has just revealed the New Generation SOPHiA DDM™ Platform, aiming to stay at the forefront of precision medicine and address today the healthcare needs of tomorrow. ...
CD Genomics, a well-established leader in transcriptome solutions, is pleased to announce the introduction of Ribosome Profiling technology. ...
sgRNA based genetic screens provide a robust platform for functional genomics, promoting research in fields such as oncology, immunology, and molecular biology. ...
Introduction Since the completion of the Human Genome Project, genomics has played an increasingly critical role in the biomedical field. ...
Personalised medicine promises to transform healthcare with treatments tailored to a patient’s unique genetic profile (genomics) and by leveraging their genomic data to predict drug targets that will improve treatment outcomes (pharmacogenomics). ...
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Denget al. report on a technique called spatial-CUT&Tag for genome-wide profiling of histone modifications pixel by pixel on a frozen tissue section without dissociation. ...
Over time, genetic research have recognized a number of genetic danger variants related to neurodegenerative problems and helped reveal new organic pathways and genes of curiosity. Nevertheless, genetic danger variants generally reside in non-coding areas and should regulate distant genes reasonably than the closest gene, in addition to a gene’s interplay companions in organic networks. ...
In order to dissect the initiation of early organogenesis at the whole embryo scale, it is desirable to not only measure genome-wide molecular profiles for cell type identification but also interrogate spatial organization in the tissue context with high spatial resolution. ...