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Hemodynamic Articles & Analysis
13 articles found
The evaluation of cardiovascular toxicity is a significant challenge in drug development. Preclinical evaluation of cardiovascular safety involves a multifaceted approach, encompassing a plethora of in vitro and in vivo endpoints. These assessments continuously evolve, aiming to mitigate the incidence of cardiovascular toxicity that may emerge during clinical trials. To shed light on the ...
According to literature, at least 30% of cases are classified as indeterminate[2], which means that a significant number of patients are likely to require additional invasive hemodynamic testing that is technically complex, costly, and increases risk for the patient. ...
According to the 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure, the criteria for diagnosing HFpEF includes: a normal or near-normal left ventricular ejection fraction (LVEF ≥50%), evidence of cardiac dysfunction by echocardiography (e.g., abnormal left ventricular filling and elevated filling pressures), and elevated natriuretic peptides.[2] The sensitivity, however, varies ...
These strategies can be classified mechanistically based on the way in which they intend to improve central hemodynamics, increase renal perfusion, remove salt and water from the body to achieve clinically meaningful degrees of decongestion. ...
Limiting the effect of Paw on hemodynamics is especially important in infants with CHD and RV dysfunction. ...
Our findings suggest that arteriovenous TEVGs develop only a mild form of venous intimal hyperplasia, which results from the typical hemodynamic changes that are associated with arteriovenous settings. Keywords Tissue-engineered vascular graft • Intimal hyperplasia • Arteriovenous graft · Remodeling · Blood flow rate· Noninflammatory Introduction ...
The addition of continuous cardiac output monitoring provides advanced hemodynamic data that helps the anesthesia and surgical teams manage the patient throughout this high-risk procedure. ...
Protamine is a standard therapy during CABG surgery and hemodynamic responses (i.e., small decreases in systemic blood pressure) to protamine are common. ...
Argos provided data that consistently showed the subtle changes in hemodynamics helping to inform decisions for a more targeted ...
These favorable in-vivo results, with excellent hemodynamic behavior and stable long-term function even in the absence of anticoagulants, demonstrate that this valve can proceed to first-in-human studies. ...
The need for providing dialysis to patients in the ICU has increased overtime. Delivery of this care is challenging to health care systems (HCS) both in costs and ...
She fared well until September 2017, when she presented with right lower extremity ulcers and pain involving D1 and D2 (Figure 1). Hemodynamic assessment at that time revealed a noncompressible ankle-brachial index (ABI), with a toe-brachial index (TBI) of 0.28, a toe pressure of 32 mm Hg, and flat digital waveforms (Figure 2). ...
Hextend bolus (500 mL) was subsequently rapidly infused using a standard pressure bag along with the addition of maintenance fluids to maintain blood pressure. Hemodynamic parameters were recorded every 10 minutes and additionally at critical time points defined in the protocol. ...