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Histology Articles & Analysis: Older

52 articles found

Speeding Up The Cancer Drug Discovery Process with Zebrafish Disease Models

Speeding Up The Cancer Drug Discovery Process with Zebrafish Disease Models

Likewise, more than 130 different genes in zebrafish liver tumors exhibited expression similar to those characteristic of human liver cancers, correlating with histological tumor type, grade, and stage. There are several approaches to generate human cancers in zebrafish, such as the development of mutant and transgenic cell lines and transplantation of tumor cells, each with ...

ByCreative Biogene


From Data to Decisions, Faster than Ever: Pioneering the future of precision medicine with the New Generation SOPHiA DDM Platform

From Data to Decisions, Faster than Ever: Pioneering the future of precision medicine with the New Generation SOPHiA DDM Platform

In response to the emerging needs in global healthcare, SOPHiA GENETICS has just revealed the New Generation SOPHiA DDM™ Platform, aiming to stay at the forefront of precision medicine and address today the healthcare needs of tomorrow. ...

BySOPHiA Genetics


In Vitro and In Vivo Characterization of BiFORM Bioactive Moldable Matrix

In Vitro and In Vivo Characterization of BiFORM Bioactive Moldable Matrix

Posterolateral Rabbit Spinal Fusion Study I. Introduction Autologous bone has long been the gold standard for bone graft substitute in spinal fusion procedures. The limited supply and morbidity associated with using autologous graft material led to the development of alternative bone grafting materials. Bioactive glass has a long history of biomedical use and has been shown to facilitate mineral ...

BySanara MedTech Inc.


ACTIGEN Verified Inductive Bone Matrix and Autologous Blood by CellRight Technologies

ACTIGEN Verified Inductive Bone Matrix and Autologous Blood by CellRight Technologies

Every lot of ACTIGEN™ Verified Inductive Bone Matrix is verified for osteoinductivity post sterilization as a condition for distribution. In-vivo test results have histologically demonstrated the presence of all 5 bone-forming elements (Chondrocytes, Osteocytes, Bone Marrow Cells, Cartilage, and New Bone). ...

BySanara MedTech Inc.


How to Detect Collagen Protein

How to Detect Collagen Protein

It binds to collagen fibers, making the fibers appear bright red under the microscope. It is often used in histological studies for collagen localization and quantification.Soluble Collagen Determination Based on Sirius RedIn addition to tissue staining, sirius red can also be used to determine the concentration of collagen in solution. ...

ByMtoZ Biolabs


The Potential of WNT/B-Catenin Modulation in Treating Pulmonary Fibrosis

The Potential of WNT/B-Catenin Modulation in Treating Pulmonary Fibrosis

Pulmonary fibrosis, particularly idiopathic pulmonary fibrosis (IPF), represents a significant challenge in healthcare due to its detrimental impact on lung function and limited treatment options. While WNT/β-catenin signaling plays a crucial role in lung development and maintenance of adult lung stem cells, its dysregulation has been associated with pulmonary fibrosis. However, recent ...

BySCIREQ - an emka TECHNOLOGIES Company


Unraveling the IL-17 Family and its Receptor Complex: Key Players in Immune Responses

Unraveling the IL-17 Family and its Receptor Complex: Key Players in Immune Responses

Allergic asthma animal models show that inhibiting IL-17E with neutralizing antibodies significantly reduces bronchial hyperresponsiveness, serum IgE concentrations, and histological features in inflammatory responses. Similarly, IL-17E is also strongly expressed in atopic eczema [3]. ...

ByBeta Lifescience


The latest developments of Medis QFR

The latest developments of Medis QFR

For further read: http://doi.org/10.1016/j.jcin.2022.07.008 Relation between coronary plaque composition assessed by intravascular ultrasound virtual histology and myocardial ischemia assessed by Quantitative Flow Ratio Dr. ...

ByMedis Medical Imaging Systems B.V.


Tips & Tricks to Optimize Your Tissue Processing

Tips & Tricks to Optimize Your Tissue Processing

Since the 19th century, the practice of tissue processing has remained largely unchanged, resulting in solidified, paraffin-embedded tissue blocks for sectioning. As staining procedures have advanced and immunohistochemistry is becoming more widely used, high-quality tissue sections are paramount for accurate interpretation of disease ...

ByQuartzy Inc.


Spatial profiling of chromatin accessibility in mouse and human tissues

Spatial profiling of chromatin accessibility in mouse and human tissues

Unsupervised clustering identified eight main clusters, that revealed distinct spatial patterns that agreed with the tissue histology (Fig. 2a–c and Extended Data Fig. 2). For example, cluster 1 represents the fetal liver and cluster 2 is specific to the spine region, including dorsal root ganglia (DRG) with chromatin accessibility for Sox10 (Supplementary Fig. 2a,b,i,j). ...

ByAtlasXomics Inc.


A Novel Potential Target for CAR-T Cell Therapy in Human Solid Tumors Discovered

A Novel Potential Target for CAR-T Cell Therapy in Human Solid Tumors Discovered

Researcher Conejo-Garcia said that given that OR2H1 can be expressed in a variety of histological solid tumor subtypes (including high-grade serous ovarian cancer, lung adenocarcinoma, cholangiocarcinoma, prostate cancer and ovarian cancer with other histological characteristics, etc.), the results of this study confirm that this novel therapy may have some ...

ByCreative BioMart


Susceptibility of ePTFE vascular grafts and bioengineered human acellular vessels to infection

Susceptibility of ePTFE vascular grafts and bioengineered human acellular vessels to infection

Two weeks later, the implant sites were scored for abscess formation and explanted materials were halved for quantification of microbial recovery and histological analyses. Results: The ePTFE implants had significantly higher abscess formation scores f Results: The ePTFE implants had significantly higher abscess formation scores for both S. aureus and E. coli inoculations ...

ByHumacyte, Inc.


Clinical implementation of the Humacyte human acellular vessel: Implications for military and civilian trauma care

Clinical implementation of the Humacyte human acellular vessel: Implications for military and civilian trauma care

In these studies, HAV sections were taken during routine procedures and subjected to histological analysis which revealed the HAV is permissive to infiltration of host cells, modifying into a multi-layered living structure mimicking the native vasculature. ...

ByHumacyte, Inc.


An Early Study on the Mechanisms that Allow Tissue-Engineered Vascular Grafts to Resist Intimal Hyperplasia

An Early Study on the Mechanisms that Allow Tissue-Engineered Vascular Grafts to Resist Intimal Hyperplasia

Intimal hyperplasia in the outflow vein of TEVGs was assessed at the anastomosis and at juxta-anastomotic regions via histological analysis, and was compared to intimal hyperplasia with polytetrafluoroethylene (PTFE) grafts in the baboon model and in literature reports from other animal models. Less venous intimal hyperplasia was observed in histological sections ...

ByHumacyte, Inc.


Arterial reconstruction with human bioengineered acellular blood vessels in patients with peripheral arterial disease

Arterial reconstruction with human bioengineered acellular blood vessels in patients with peripheral arterial disease

Early clinical experience with these vessels, in the arterial position, suggest that they are safe, have acceptable patency, a low incidence of infection, and do not require the harvest of autologous vein or any cells from the recipient. Histologic examination of tissue biopsies revealed vascular remodeling and repopulation by host cells. ...

ByHumacyte, Inc.


How 4D Path and PathPresenter aim to further AI-enabled digital pathology for breast tumor profiling

How 4D Path and PathPresenter aim to further AI-enabled digital pathology for breast tumor profiling

The digital pathology software company PathPresenter (Montville, New Jersey) and the precision oncology platform firm 4D Path have entered into a partnership that could improve the diagnostic accuracy of breast tumor profiling. PathPresenter has developed a digital workflow tool for clinicians, pathologists and pharma companies to aggregate medical data. ...

By4D Path Inc.


Exercise in the morning or in the evening has a completely distinct effect!   

Exercise in the morning or in the evening has a completely distinct effect!  

Following the exercise, tissues from various parts of the mice were collected, including serum, skeletal muscle, liver, epididymal white adipose tissue (eWAT), inguinal subcutaneous white adipose tissue (iWAT), and interscapular brown adipose tissue (BAT), and the metabolites and gene expression status of these tissues were histologically analyzed. Each tissue displayed a ...

ByCreative Biolabs


Segmentation of the Main Structures in Hematoxylin and Eosin Images

Segmentation of the Main Structures in Hematoxylin and Eosin Images

This process includes gathering ground truth data and the outputs of our algorithm on that data. The histology slides were scanned on a Hamamatsu NanoZoomer C9600. These histology samples were obtained from breast tissue. ...

ByVirasoft Inc.


Five Year Outcomes in Patients with End Stage Renal Disease Who Received a Bioengineered Human Acellular Vessel for Dialysis Access

Five Year Outcomes in Patients with End Stage Renal Disease Who Received a Bioengineered Human Acellular Vessel for Dialysis Access

This report contains the follow up functional and histological data on 29 of the original 40 patients who demonstrated HAV function at the 24 month time point. ...

ByHumacyte, Inc.


West Hertfordshire IBD technology study - Case Study

West Hertfordshire IBD technology study - Case Study

This is an IBD technology study investigating quantitative metrics for endoscopy, histology and radiology for improved diagnosis and assessment of ...

ByPerspectum

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