In Vitro Cell Articles & Analysis
33 articles found
When administered, the RDCs selectively bind to the cancer cells, allowing for localized delivery of radiation. The development of RDCs involves biochemistry, molecular biology, and radiology. ...
Astrocytes, the star-shaped glial cells in the brain, play crucial roles in maintaining homeostasis, supporting neuronal function, and responding to injury. ...
The corneal epithelium consists of several layers of cells, primarily composed of keratinocytes. These cells are characterized by their ability to rapidly proliferate and differentiate, ensuring a constant renewal of the epithelial layer. ...
In cancer research, zebrafish models have advantages over traditional cell culture assays because a wider range of phenotypes can be tested. ...
By offering a unique combination of biological complexity and controlled experimental conditions, PCLS serve as a critical bridge between the limitations of traditional in vitro cell cultures and the complexities of in vivo models. The versatility and precision of this technique have positioned PCLS as an invaluable tool in advancing our understanding of lung ...
By creating cell banks of in vitro immortalized, primary-like cells from different tissues and donors with diverse genetic backgrounds, you are enable to perform their research on more than one individual cell line. ...
Mitochondria, often referred to as the powerhouses of the cell, are responsible for generating energy in the form of adenosine triphosphate (ATP). ...
It plays an essential role in providing a scaffold for cellular support and thereby affecting cell attachment, migration, proliferation, differentiation, and survival. ...
These models include in vivo animal models, in vitro cell culture models, in silico (computer-based) models, and genetically modified organism models. ...
These models stem from animal models to in vitro and in silico models, each playing a unique role in observing the disease. ...
Classes of Cell-Penetrating Peptides There are many types of cell-penetrating peptides (CPPs), and their classification is based on physicochemical properties, sources, intake mechanisms, and biomedical applications. ...
These models stem from animal models to in vitro and in silico models, each playing a unique role in observing the disease. ...
Since 1,3-β-D-glucan is an important component of fungal cell walls, rezafungin disrupts the cell walls of fungal species including Candida and acts as a concentration-dependent fungicide in vitro. Mammalian cells do not express β-1-3-glucan synthase, therefore, the action of rezafungin is specific to fungi. 3. ...
In fact, it is not difficult to see that these advanced technologies are all related to cell culture. In order to maintain efficient growth, proliferation, and differentiation during in vitro cell culture, many cell cultures require the addition of various cytokines. Cytokines Backgrounds Cytokines are proteins synthesized and ...
In addition, a majority of living cells cannot be cultivated in vitro, single-cell RNA-seq may discover novel species or regulatory processes of biotechnological or medical relevance. The workflow of single-cell RNA-seq generally involves the following steps: single-cell isolation, cDNA library construction, ...
Therefore, researchers are constantly trying new ways to change its ability to enter cells. Yuhuan Li and his colleagues constructed a novel siRNA delivery system, sTOLP, which was based on cell-penetrating peptide oleoyl-octaarginine (OA-R8) modified multifunctional lipid nano-particles. ...
Proteins in nature are composed of 20 kinds of natural amino acids, and the protein synthesis mechanism of cells uses 64 kinds of gene codons to complete the protein synthesis process. The self-expanding technology of genetic code pairs specific codons with unnatural amino acids, allowing cells to add unnatural amino acids at specific sites when synthesizing ...
Genetic mutations in cells are an important cause of cancer development, progression, and drug resistance. ...
Both the in vivo gene editing therapy and in vitro TCR-T cell therapy utilize LNP-delivered CRISPR-Cas9 for gene editing. ...
Novel cytotoxic drugs New cytotoxic drugs have been developed to target cancer cells with low antigen expression or resistance to auristatins or maytansinoids. ...