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In Vivo Cell Articles & Analysis: Older

11 articles found

Enhancing CAR-T Cell Detection with CABR™ ISH Probes

Enhancing CAR-T Cell Detection with CABR™ ISH Probes

The emergence of chimeric antigen receptor T-cell (CAR-T) therapy has revolutionized the treatment of certain cancers, providing a promising targeted approach to eliminate cancer cells. However, the monitoring and detection of CAR-T cells in vivo remain a challenge in the evaluation of treatment efficacy. ...

ByCreative Bioarray


Exploring the Origins and Categorization of Microneedles

Exploring the Origins and Categorization of Microneedles

This refers to a cryomicroneedle shorter than 1 mm, which is loaded and stored with living mammalian cells in vivo and delivers therapeutic cells into the skin layer. When administering the drug, the patch-shaped device loaded with cryomicroneedle arrays is placed on the skin, and the cryomicroneedles penetrate into the skin, detach from the base ...

ByCD Formulation


Research Progress of Tetrahydrocurcumin

Research Progress of Tetrahydrocurcumin

Tetrahydrocurcumin (THC), as the most active and main metabolite produced in the metabolism of curcumin in vivo, can be isolated from the cytoplasm of the small intestine and liver after curcumin administration in human or mouse. ...

ByHunan Huateng Pharmaceutical Co. Ltd.


CAR-T Cell Anti-Cancer Therapy Ushered in A Revolutionary Breakthrough!

CAR-T Cell Anti-Cancer Therapy Ushered in A Revolutionary Breakthrough!

This conditioning regimen may improve the proliferation and durable viability of adoptive T cells in vivo by balancing cytokine production in vivo and removing some immunosuppressive cells (such as regulatory T cells and myeloid-derived suppressor cells) in vivo. ...

ByCreative BioMart


Chemyx Syringe Pumps in Neuroscience Research

Chemyx Syringe Pumps in Neuroscience Research

Introduction The classical field of neuroscience entails biological or psychological investigation of the nervous system, including the brain, spinal cord and the systemic network of sensory nerve cells called neurons.1 Traditionally, this field comprised of purely biological studies but has since flourished into an interdisciplinary sphere addressing the developmental, ...

ByChemyx Inc


Application of refractable nanocomposite on cell based therapy in central nervous system

Application of refractable nanocomposite on cell based therapy in central nervous system

Quantum Dots (QDs) are nano–particles carrying high stability fluorescence to follow the grafted cells which can be used in investigating the movement of cells and understanding the organogenesis of stem cells during development and wound repair processes in adulthood. For its easy acquirement and bypassing moral ethical issues, it makes the ...

ByInderscience Publishers


Detection of trace cobalt ions in <italic>in vivo</italic> plant cells using a voltammetric interlocking system

Detection of trace cobalt ions in <italic>in vivo</italic> plant cells using a voltammetric interlocking system

This experiment was conducted to establish a system for detecting trace cobalt ions in water and plant tissues using a voltammetric in vivo sensor. Cyclic and stripping voltammetry was devised from hand-made, macro-type implantable three-electrode systems. The results reached micro and nano working ranges at 100 sec accumulation time. The statistical detection limit (S/N) was attained at 6.0 ng ...

ByIWA Publishing


Augmentation of anti–tumour activity of cisplatin by pectin nano–conjugates in B–16 mouse model: pharmacokinetics and in–vivo biodistribution of radio–labelled, hydrophilic nano–conjugates

Augmentation of anti–tumour activity of cisplatin by pectin nano–conjugates in B–16 mouse model: pharmacokinetics and in–vivo biodistribution of radio–labelled, hydrophilic nano–conjugates

Nanoconjugates have matured from simple devices to multifunctional, biodegradable, non–toxic and non–immunogenic constructs, capable of delivering synergistically functioning drugs in vivo. The present study evaluates the efficacy of drug polymer self folding nano–conjugates of pectin–cisplatin to enhance blood circulating levels of cisplatin. ...

ByInderscience Publishers


Growth and behaviour of bovine articular chondrocytes on nanoengineered surfaces: Part I

Growth and behaviour of bovine articular chondrocytes on nanoengineered surfaces: Part I

Surface modification, using biomaterials to mimic in vivo cell microenvironment, plays an important role in tissue engineering. ...

ByInderscience Publishers


Investigation of the low-dose γ-irradiation effect on the spontaneous and high-dose radiation-induced level of cytogenetic damage in mouse bone marrow cells in vivo

Investigation of the low-dose γ-irradiation effect on the spontaneous and high-dose radiation-induced level of cytogenetic damage in mouse bone marrow cells in vivo

The effect of low-dose gamma-irradiation (0.1 or 0.2 Gy with a dose rate of 0.125 Gy/min) of mice on the spontaneous and high-dose radiation-induced level of cytogenetic damage during ageing of animals was studied using the micronucleus test. It was shown that a single low dose of gamma-radiation induces a cytogenetic adaptive response in mouse bone marrow cells, which persists for up to 12 ...

ByInderscience Publishers


Cyclin D1 Genetic Heterozygosity Regulates Colonic Epithelial Cell Differentiation and Tumor Number in ApcMin Mice

Cyclin D1 Genetic Heterozygosity Regulates Colonic Epithelial Cell Differentiation and Tumor Number in ApcMin Mice

Cyclin D1 deficiency reduced DNA synthesis and induced differentiation of colonic epithelial cells harboring mutant APC but not wild-type APC cells in vivo. In previous studies, the complete loss of cyclin D1 through homozygous genetic deletion conveyed breast tumor resistance. ...

ByAmerican Society for Microbiology (ASM)

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