Intestinal Barrier Articles & Analysis
6 articles found
Types of In Vitro Permeability Assays Various methods are employed in in vitro permeability assays, each suited for different purposes: Caco-2 Cell Model: This assay uses human intestinal epithelial cells, which mimic the intestinal barrier. The permeability of compounds is evaluated by measuring the transport across this cell monolayer, ...
The intestinal microbes are able to regulate dietary lipid composition, digestion and absorption and may alter the formation of intestinal lipoproteins. ...
Serum DAO is elevated in small intestinal mucosal barrier failure or in intestinal mucosal cell necrosis; therefore, DAO activity in blood can reflect the state of intestinal injury. ...
Tumor Necrosis Factor Alpha (TNF-a) is a potent cytokine that is over-expressed by cells during chronic intestinal inflammation. Furthermore, TNF-a represents the most validated clinical target for ulcerative colitis (UC) and inflammatory bowel diseases (IBD) with multiple emerging neutralizing/inflammation-reducing therapeutics targeting this cytokine for inactivation. TNF-a ...
The large intestine is composed of intestinal epithelial cells (IECs), which form an intestinal barrier between the microbiota in the intestinal lumen and surrounding tissues. ...
Probiotics can reduce the risk of liver cancer by regulating the host intestinal flora to prevent endotoxemia associated with dysbacteriosis, maintaining the intestinal epithelial barrier function, and inhibiting the translocation of intestinal bacteria and their derivatives into the body circulation. ...