Neuropathic Pain Articles & Analysis
10 articles found
The functional role of lncRNAs in a variety of neuropathic pain and neurological disorders is increasingly recognized. ...
Peripheral nerve injury can result in the formation of neuroma/nerve entrapment, a persistent peripheral neuropathic pain state which is often refractory to invasive interventions or medications. Therefore, there is a need in the field of pain management to develop innovative noninvasive therapy in treating post-traumatic peripheral ...
On the other hand, firing of smaller pain transmitting fibers such as A-dclta and C-fibcrs is enhanced. This aberrant afferent neuronal behavior is thought to be one of the main neuronal mechanisms leading to development of chronic posttraumatic peripheral neuropathic pain (PTP-NP) [Puig and Sorkin, 1996). Clinically, this persistent peripheral ...
Tetrahydrocannabinol (THC) Tetrahydrocannabinol (THC) is an active ingredient in Nabiximols, a specific extract of Cannabis that was approved as a botanical drug in the United Kingdom since 2010 as a mouth spray for people with multiple sclerosis to reduce neuropathic pain, spasticity, overactive bladder, and other symptoms. Nabiximols (as Sativex) is available ...
My role as a Research Scientist is quite dynamic where my day-to-day duties can vary greatly from R&D projects to product manufacture, and from inventory and laboratory management roles to neuropathic pain preclinical trial designs. I have been heavily involved in the Regeneus pain project after Regeneus received an ARC Linkage Grant with ...
So, we have a non-opiate pain reliever for both somatic sensory pain and neuropathic pain. This is important because it is working to solve a huge unmet medical need — there is currently nothing else like this on the market, and we think we finally have one. ...
Our lead platform technology Progenza™ contains both MSCs and their bioactive secretome for an ideal therapeutic effect that treats symptoms of pain and inflammation and also promotes tissue repair. Our second technology platform, Sygenus, utilises the bioactive secretome of MSCs only, and works as a topical treatment for pain and inflammation, as well as ...
Everyone at some time in their life has suffered from the throbbing, aching, and annoying pain of a headache. Headaches can be mild, or they can be severe and even debilitating. While most people experience a headache occasionally, others deal with recurrent head pain, sometimes experiencing headaches weekly, or even up to 15 or more times each month, as in the case of chronic ...
However, setting our sights to the future, we also want to keep growing our therapy business by supporting our installed NBT® system base in the US and to support new sales in Europe, where NBT® is approved also for the treatment of chronic neuropathic pain. In fact, we plan to evaluate new pilot clinical trials for chronic pain and with ...
“Interestingly enough, you have to realize that neuropathic pain has several components, several phases. One of the initial ones is just a reaction to the drug itself, which is basically an oxidative stressor,” Brenneman said. ...