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Pancreatic Articles & Analysis
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For instance, metformin, a biguanide, is renowned for reducing glucose production in the liver, while sulfonylureas stimulate insulin production from pancreatic beta cells. Consequently, the availability of these APIs has transformed the landscape of diabetes treatment, making it possible to tailor therapies to individual patient needs, thereby enhancing treatment outcomes and ...
The company’s focus spans various cancer types, including bladder cancer, breast cancer, and pancreatic cancer, among others. By specializing in diverse drug development services and therapeutic methodologies, Alfa Cytology is poised to make significant contributions to the field of oncology and continues to expand its capabilities in response to the evolving demands of cancer ...
The Biological Function of Elastase Elastase is primarily produced by the pancreas and certain types of white blood cells, including neutrophils and macrophages. In the digestive system, pancreatic elastase is secreted into the small intestine, where it breaks down dietary proteins to facilitate nutrient absorption. ...
Alfa Cytology has announced pancreatic cancer vaccine development services to improve the efficacy and safety of related vaccines. Alfa Cytology, a biotech company composed of scientists, bioinformatics, and oncologists, has recently announced its pancreatic cancer vaccine development services to provide further strategies for cancer therapy research. ...
Alfa Cytology has announced tumor models customization service for pancreatic cancer research. Alfa Cytology, a biotech company specializing in cancer research, has recently unveiled the service on pancreatic cancer tumor model customization to dig into the generation and development of pancreatic cancer and correspondingly provides customized ...
Influence of 3D tumor cell/fibroblast co-culture on monocyte differentiation and tumor progression in pancreatic cancer. Diss. Universität Würzburg, 2017. Kartikasari, Apriliana ER, et al. ...
Influence of 3D tumor cell/fibroblast co-culture on monocyte differentiation and tumor progression in pancreatic cancer. Diss. Universität Würzburg, 2017. Kartikasari, Apriliana ER, et al. ...
The drug SN38 shows tremendous efficacy against a variety of cancers including colorectal, lung, and pancreatic cancer. However, issues like poor aqueous solubility and systemic toxicity have limited its use. ...
These oral antidiabetic medications mainly work by increasing insulin sensitivity, slowing down the metabolism of carbohydrates in the small intestine, repairing and improving the function of pancreatic β-cells, and promoting insulin secretion to achieve blood glucose reduction. ...
As the emulsified fat droplets are further broken down by pancreatic lipases, bile acids swoop in to encapsulate the resulting lipid fragments. ...
Diabetes, specifically Type 1 and Type 2 Diabetes Mellitus, remains one of the most commonly encountered metabolic diseases worldwide. The complexity and diversity of these conditions necessitate the development of detailed medical models for a comprehensive understanding of the diseases. Over time, Type 1 and Type 2 Diabetes Mellitus Models, Metabolic Disease Models, and generalized Diabetes ...
Applications in the Pharmaceutical Industry Digestive Disorders: Native Porcine Pancreatin is crucial in the treatment of digestive disorders, such as cystic fibrosis and chronic pancreatitis. Individuals with these conditions often suffer from insufficient endogenous enzyme production. ...
The distinct role of CD73 in the progression of pancreatic cancer. J Mol Med (Berl). 2019 Jun;97(6):803-815. doi: 10.1007/s00109-018-01742-0. ...
Trop-2 protein is highly expressed in a variety of tumors, such as pancreatic cancer, breast cancer, colon cancer, ovarian cancer, and non-small cell lung cancer. ...
What is cystic fibrosis? Cystic fibrosis (CF) is a rare genetic disorder that affects the lungs, digestive system, and other organs. It is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which encodes a protein that regulates chloride ions transport across cell membranes. These mutations cause the CFTR protein to be either absent or not function ...
Diabetes is a chronic disease that affects more than 540 million people worldwide and is one of the leading causes of death and disability worldwide. In China, there are more than 114 million adults with diabetes, accounting for about a quarter of the world's diabetes patients. With the change of living and eating habits, diabetes has become the third major factor affecting human health after ...
The expression of IL-17B in the synovium and pancreatic tissue of patients with rheumatoid arthritis (RA) increases, and IL-17B enhances the effect of TNF-α in fibroblasts, which may be important for the immune formation.Look at "IL-17 Family Ligands" and "IL-17 Receptor Family" below for full details on IL-17 ligands and receptors. ...
FGL2 and disease Studies have found that FGL2 is highly expressed in microvascular endothelial cells, causing microcirculatory disturbance, promoting myocardial and liver ischemia-reperfusion injury, arthritis, type 2 diabetic heart failure, and type 2 diabetic nephropathy; FGL2 is highly expressed in inflammatory bowel disease mucosa , correlated with disease severity; in HCV, NAFLD, acute ...
However, abnormal expression of Nectin-4 has been observed in several common cancer types, including bladder cancer, breast cancer, lung cancer, pancreatic cancer, and ovarian cancer. In the PI3K-AKT signaling pathway, Nectin-4 promotes cancer cell proliferation and metastasis by activating WNT-β-catenin and Rac small G proteins. ...
TSLP and cancer New functions of TSLP have been discovered in the induction and progression of various tumors, including solid tumors such as breast, colon, and pancreatic cancers, as well as hematological malignancies like B-cell acute lymphoblastic leukemia (B-ALL). ...