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Patients With Advanced Her2 Positive Articles & Analysis: Older

28 articles found

Diabetomics Lumella - New Point-of-Care Blood Test Kit for Early Detection of Preeclampsia

Diabetomics Lumella - New Point-of-Care Blood Test Kit for Early Detection of Preeclampsia

Abstract Background: Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation of synovial joints. Anticitrullinated protein autoantibodies are detected by the CCP test in early disease and predict the development of erosive disease as well as extraarticular manifestations. We recently reported that many RA patients have anti-citrullinated albumin (ACA) ...

ByDiabetomics, Inc.


Huateng Pharma Supplies Some Intermediates of CDK4/6 Inhibitors for Treatment of Advanced Breast Cancer

Huateng Pharma Supplies Some Intermediates of CDK4/6 Inhibitors for Treatment of Advanced Breast Cancer

While breast cancer rates are higher among women in more developed regions, rates are increasing in nearly every region globally. The majority of patients with metastatic breast cancer (MBC) have hormone receptor-positive HER2-negative disease. ...

ByHunan Huateng Pharmaceutical Co. Ltd.


ADC Drugs For HER2 Positive Breast Cancer

ADC Drugs For HER2 Positive Breast Cancer

It will be listed in China in 2020, it has been approved for adjuvant therapy in HER2-positive early breast cancer patients with residual invasive lesions (non-pCR) after receiving taxane combined trastuzuab-based neoadjuvant therapy and for monotherapy in HER2-positive, unresectable locally ...

ByHunan Huateng Pharmaceutical Co. Ltd.


FDA Approved ALK Inhibitors for ALK-Positive Non-Small Cell Lung Cancer

FDA Approved ALK Inhibitors for ALK-Positive Non-Small Cell Lung Cancer

Lung cancer is a major type of cancer in the world, with the highest morbidity and mortality among all malignant tumors. ALK-positive non-small cell lung cancer (ALK+ NSCLC) is a relatively rare and dangerous subtype, with patients suffering from a high incidence rate of brain metastases. Statistics show that about 55% of ALK-positive advanced NSCLC patients will develop brain metastases during ...

ByBOC Sciences


Clinician Attitudes are Shifting on MRD-guided Decision Making in Multiple Myeloma

Clinician Attitudes are Shifting on MRD-guided Decision Making in Multiple Myeloma

This September marks four years since the 2018 Food and Drug Administration clearance for clonoSEQ to detect and monitor minimal residual disease (MRD) in bone marrow from patients with acute lymphoblastic leukemia (ALL) and multiple myeloma (MM). In the years following, researchers have explored the value of using MRD status to guide treatment in blood cancers – and the mounting ...

ByAdaptive Biotechnologies


Extentrac Elite Case - Case study

Extentrac Elite Case - Case study

Clinical Study Report A practice based prospective study of 31 consecutive patients (21 men, 10 women – mean age 57 years) with low back pain with or without radiculopathy. Each patient completed the Oswestry Low Back Pain Disability Questionnaire (Ver.2) and the Numeric Rating Scale (NRS-11) – pre and post treatment. Disability assessment was based upon an absolute percentage point ...

BySpine Care Technologies, Inc.


Spine-Intra-Abdominal Pressure (SIAP) - Case Study

Spine-Intra-Abdominal Pressure (SIAP) - Case Study

The SIAP study investigates the effect of using Ergotrics' Inflatable Prone Support (IPS) on intra-abdominal pressure (IAP) during spine surgery. Study background The objective of this study is to demonstrate the ability of the inflatable Prone Supports (IPS) to lower the IAP of patients in the prone position. Whenever the patients’ position is changed to prone, the IAP is increased due to ...

ByErgotrics NV


Zanidatamab, a HER2-targeted bispecific antibody, in combination with docetaxel as first-line therapy for patients with advanced HER2-positive breast cancer: Preliminary results from a Phase 1b/2 study (American Society of Clinical Oncology)

Zanidatamab, a HER2-targeted bispecific antibody, in combination with docetaxel as first-line therapy for patients with advanced HER2-positive breast cancer: Preliminary results from a Phase 1b/2 study (American Society of Clinical Oncology)

Worldwide, breast cancer is the most commonly diagnosed cancer and the leading cause of cancer deaths in women, with over 650,000 deaths in 2020.1,2 Human epidermal growth factor receptor 2 (HER2)-targeted agents have improved outcomes in HER2-positive breast cancer, but most patients in first-line therapy do not respond to current therapies, eventually relapse or develop ...

ByZymeworks Inc


Micromate™ Case Report: Robot-Guided Bone Biopsy

Micromate™ Case Report: Robot-Guided Bone Biopsy

Micromate™ Case Report series presents real cases performed by the physicians currently using our full-fledged robotic platform for percutaneous procedures. Today, we join Dr. Alexander Kupferthaler, Interventional Radiologist at the Ordensklinikum Linz – Barmherzige Schwestern, for a robot-guided bone biopsy. Clinical Context 65-year-old female with invasive lobular carcinoma of ...

ByInterventional Systems (iSYS)


How IFIX Can Help With Contrast Shortage

How IFIX Can Help With Contrast Shortage

Why is there a shortage of CT contrast? The COVID-19 pandemic continues to be the root cause of disruptions in the global supply chain. This time, it led to the temporary shutdown of a production facility in Shanghai, creating a severe shortage of iodinated contrast media (ICM) and affecting imaging facilities – especially in the US, with the American Hospital Association expressing its ...

ByInterventional Systems (iSYS)


Infiltrating Ductal Carcinoma (IDC) - Case Study

Infiltrating Ductal Carcinoma (IDC) - Case Study

Patient with positive family history of breast cancer and ovarian cancer. September 2003 mammogram reported benign micro calcifications. August 2007 patient presented with a palpable mass in lateral aspect of left ...

ByAurora Healthcare US Corp.


Diagnostic Radiology Consultants - Chattanooga - TN- Case Study

Diagnostic Radiology Consultants - Chattanooga - TN- Case Study

CAD PRO® Advantage Digitizer Provides Mammography Workflow Solution for Innovative Radiology Practice. For more than 50 years, Diagnostic Radiology Consultants (DRC) has pioneered imaging services in the tri-state area of Tennessee, Georgia, and Alabama. The innovative group, including 11 radiologists at 12 sites, often is the first to offer emerging technologies that positively impact ...

ByVIDAR Systems Corporation


Importance of hemodynamic monitoring during esophagectomy - Case Study

Importance of hemodynamic monitoring during esophagectomy - Case Study

Background Esophagectomy for cancer involves two- or three-phase procedures, such as abdominal, chest and/or neck incisions, is more invasive than other types of gastrointestinal surgery, and is associated with high risk for postoperative morbidity. Because of this risk, perioperative management of circulatory conditions such as hypovolemic hypotension is especially important to avoid ...

ByRetia Medical, LLC


Beyond Insulin: Immunotherapy for Type 1 Diabetes-PI   

Beyond Insulin: Immunotherapy for Type 1 Diabetes-PI  

Type 1 diabetes (T1D) is a complex T-cell-mediated autoimmune disease that results in the destruction of insulin-producing beta cells and inadequate insulin secretion. Prior to the discovery of insulin in 1921, patients with T1D died within a year or two of diagnosis. Since the discovery and mass production of insulin, T1D is no longer a terminal disease. However, over time, many patients still ...

ByCreative Biolabs


Micromate™ Case Report: Robot-Guided Type II Endoleak Embolization

Micromate™ Case Report: Robot-Guided Type II Endoleak Embolization

Micromate™ Case Report series presents real cases performed by the physicians currently using the world’s smallest robot for percutaneous procedures. Today, we join Drs. Gerlig Widmann and Martin Freund, Interventional Radiologists at the Tirol Kliniken, for a robot-guided type II endoleak embolization. Clinical Context Patient’s profile: Male patient, previously subjected ...

ByInterventional Systems (iSYS)


Everything we know About AMD and Dark Adaptation

Everything we know About AMD and Dark Adaptation

When automated dark adaptometry was first commercialized, many of us had more questions than answers with regard to using this information for detecting AMD and monitoring disease progression. But with more than seven years of practical in-office experience performing dark adaptation testing on thousands of patients, the tables have turned. This technology offers a safety net for ...

ByMacuLogix


Balance Error Scoring System with force/pressure platform

Balance Error Scoring System with force/pressure platform

A look at the Balance Error Scoring System with force/pressure platform The Balance Error Scoring System (BESS) is a well-known tool to evaluate the effects of a head injury on static postural stability, or standing still in different positions. This protocol is often used in athletes after sport-related concussions or mild traumatic brain injuries (TBIs) [1]. BESS was developed by researchers ...

BySensing Future Technologies


Q&A with Prof. Graham Vesey PhD, Chief Scientific Officer and Executive Director at Regeneus

Q&A with Prof. Graham Vesey PhD, Chief Scientific Officer and Executive Director at Regeneus

Q. Tell us about your role as Chief Scientific Officer at Regeneus? A. My role at Regeneus from the beginning has been to invent and develop Regeneus’ intellectual property (IP). With over 30 years’ experience as a scientific researcher spanning fields of regenerative medicine and microbiology, I have always been focused on developing and licencing technologies to solve problems. ...

ByRegeneus Ltd.


Predictable Precision Implant Placement Using Dynamic Surgical Guidance: a Five-month Follow-up - Case study

Predictable Precision Implant Placement Using Dynamic Surgical Guidance: a Five-month Follow-up - Case study

The following case was performed at the Pacific Dental Convention’s Live Surgical Stage held March 8th, 2018 in Vancouver, BC. The patient is a healthy 58 year old male with no known allergies or medical contra-indications to dental treatment. Patient presented with a Class III malocclusion for which he received both orthodontic and oral surgery consultations; however, he was not ...

ByNavigate Surgical Technologies Inc.


Dynamic Surgical Guidance to Facilitate Dental Implant Placement

Dynamic Surgical Guidance to Facilitate Dental Implant Placement

The long-term success of dental implant surgery is dependent, in part, on accurate planning and placement of the implant.1 Currently, there are many digital planning systems available to aid the clinician in pre-operative treatment planning, although the main challenge with these planning systems is to accurately transfer the digital plan to the clinical situation. Most systems involve taking a ...

ByNavigate Surgical Technologies Inc.

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