Preclinical Research Articles & Analysis: Older
84 articles found
The service encompasses the entire preclinical development lifecycle of therapeutic antibodies—ranging from initial conceptualization and engineering to rigorous quality assurance assessments. ...
Breast cancer remains one of the most prevalent malignancies affecting women worldwide, necessitating innovative approaches for effective treatment and research. Among the most promising strategies in this endeavor are the use of tumor models for breast cancer and the development of customized antibody-drug conjugates (ADCs). ...
By utilizing premade AAV particles, researchers can bypass the complexities often associated with the production and purification of viral vectors, thus saving time and resources. The availability of premade AAV particles allows for a more accessible approach to gene therapy research. Researchers can focus on experimental design and therapeutic ...
Alfa Cytology, celebrated for its cutting-edge biotech solutions and extensive tumor research expertise, has recently introduced brain tumor drug development services, designed to empower researchers in understanding the intricacies and unique challenges associated with brain tumors. ...
Hence, an extensive lattice of regulations envelops these modalities, mandating rigorous preclinical studies and clinical trials before their eventual public deployment. ...
Transition Program for GMP Cytokines - For each cytokine, Creative Bioarray provides a certificate of analysis, stability data, and bioactivity documentation for comparison to research-grade cytokines. Customer confirms that GMP-grade cytokines of interest are produced by the same cloning and manufacturing process as research-grade cytokines. Subsequently, ...
Precision-Cut Lung Slices (PCLS) have emerged as a innovative ex vivo model that allows researchers to explore deep into lung physiology, disease mechanisms, and pharmacological responses. By offering a unique combination of biological complexity and controlled experimental conditions, PCLS serve as a critical bridge between the limitations of traditional in vitro cell cultures and the ...
CD BioSciences has launched new services on anti-centrosome antibody development to assist cancer preclinical research. It is committed to providing full packages from antigen synthesis to antibody generation and manufacturing. ...
Computer SimulationIn recent years, computer simulation technology has been increasingly used in antibody research and is often used to screen, select, and optimize potential antibody sequences after discovery activities. ...
Alfa Cytology’s team of scientists can design more effective vaccine programs, and conduct preclinical evaluations on the safety and efficiency of vaccines. Moreover, to further explore the mechanism of PC occurrence, development, invasion, and metastasis, Alfa Cytology independently developed PC model construction services, dedicated to offering different ...
Alfa Cytology has announced its small molecule drug development to advance preclinical cancer research. Alfa Cytology, a comprehensive biotech company specializing in cancer research, has recently announced the cancer small molecule drug development services. ...
Complete project procedures support a good foundation for preclinical research, and novel drugs have low cost, less toxicity, and higher safety than traditional ones. Apart from preclinical research services for pancreatic cancer, Alfa Cytology offers breast cancer therapeutic development services as well. ...
Host cell proteins (HCPs) are protein impurities produced by genetically engineered strains or cell lines. Some of these proteins are necessary for the survival, reproduction and other normal physiological activities of engineered strains or cell lines. HCPs are purified together with the target product during the production process and cannot be removed. Risks of HCPs In general, HCP ...
Ongoing research and inventions in the field of oncology focus on the development of small molecule drug therapies for use in brain tumor resection. ...
As a leading biotechnology company, MtoZ Biolabs is committed to providing comprehensive, one-stop CRO testing services to scientific research institutions and pharmaceutical companies worldwide. Whether in the early stages of drug discovery, candidate drug evaluation, or preclinical development, MtoZ Biolabs can provide professional technical support and ...
Once the target antigen is linked, researchers can begin the process of creating monoclonal antibodies that specifically bind to that antigen. ...
Hundreds of natural or synthetic compounds have been used in adjuvant research, but the number of adjuvants approved for use in vaccines remains limited. ...
Antibody drug conjugates (ADCs) are a new class of biopharmaceuticals that use monoclonal antibodies to target tumor cells to deliver potent cytotoxic drugs. So far, a total of 15 ADC drugs have been approved worldwide, of which the FDA has approved 13 ADCs for various cancers, including Adcetris®, Kadcyla®, Besponsa®, Mylotarg®, Lumoxiti®, Polivy®, Padcev®, Enhertu ®, Trodelvy® and Blenrep®. As ...
With the rapid development of antibody-drug conjugate (ADC), more and more companies have entered the field of ADC research and development, and various types of ADC technologies and branches have emerged. ...
Hence, an extensive lattice of regulations envelops these modalities, mandating rigorous preclinical studies and clinical trials before their eventual public deployment. ...