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Pulmonary Arterial Articles & Analysis

5 articles found

PCLS: An ex-vivo Window Into Lung Disease and Drug Discovery

PCLS: An ex-vivo Window Into Lung Disease and Drug Discovery

Precision-Cut Lung Slices (PCLS) have emerged as a innovative ex vivo model that allows researchers to explore deep into lung physiology, disease mechanisms, and pharmacological responses. By offering a unique combination of biological complexity and controlled experimental conditions, PCLS serve as a critical bridge between the limitations of traditional in vitro cell cultures and the ...

BySCIREQ - an emka TECHNOLOGIES Company


Diagnosing heart failure with preserved ejection fraction (HFpEF)

Diagnosing heart failure with preserved ejection fraction (HFpEF)

Physical signs of heart failure (HF) (such as elevated jugular venous pressure, pulmonary rales, and lower extremity edema) may or may not be present. [9] A history of atrial fibrillation (AF), obesity, and diabetes all increase the likelihood of HFpEF. [10] (Table 1). ...

ByUltromics Limited


Conceptual Considerations for Device-Based Therapy in Acute Decompensated Heart Failure

Conceptual Considerations for Device-Based Therapy in Acute Decompensated Heart Failure

In recent proof of concept and feasibility studies, stimulation of the nerves in the right pulmonary artery (Figure 5) for 1 hour was safe and resulted in >20% increase in contractility and a 13% increase in mean arterial pressure without an increase in heart rate (Cardionomic, Inc). ...

BySecond Heart Assist, Inc.


How Much Do You Know about Glycosaminoglycans?

How Much Do You Know about Glycosaminoglycans?

This is why they are found in synovial fluid, articular cartilage, heart valves (chondroitin sulfate, the most abundant GAG in the body), skin, pulmonary arteries and liver (heparin with anticoagulant function), tendons and lungs (dermatan sulfate) and cornea and bone (keratin ...

ByCD BioGlyco.


Remote Oncology Care: Review of Current Technology and Future Directions

Remote Oncology Care: Review of Current Technology and Future Directions

While advanced devices such as pulmonary artery pressure monitors and implantable loop recorders have proven benefits in cardiovascular care, similar options do not exist for oncology. ...

ByPAVmed Inc.

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