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Radioisotope Articles & Analysis
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In recent years, the fight against cancer has seen significant advances, particularly with the emergence of targeted therapy. Among the most promising strategies in this domain is the development of radioactive drug conjugates(RDCs). These innovative therapeutic agents combine the targeting capabilities of antibodies with the cytotoxic effects of radioactive isotopes, providing a powerful ...
The Structure of Radionuclide Drug Conjugates (RDCs) Similar to ADCs and SMDCs, RDCs are primarily composed of components that facilitate targeted localization, including antibodies or small molecules (ligands) for targeting, linkers, chelators, and radiographic/imaging factors (radioisotopes). The most significant difference between RDCs and other conjugate drugs is the drug ...
Stable isotopes of elements have similar physicochemical properties and different intranuclear properties. Compared with radioisotopes, stable isotopes have the following characteristics, including excellent sensitivity, high measurement accuracy, no radiation and less hazardous, stable properties, stable signal values, multiple isotopes can be detected at one time, and ...
When used for cancer diagnosis, PDCs can be labeled with positron-emitting radioactive isotopes (fluorine 18 (18F), copper 64 (64Cu), and gallium 68 (68Ga)) to generate PET imaging. Radioisotope-labeled PDCs can also be used therapeutically. Peptide receptor radionuclide therapy (PRRT) targets and tissue-specific radiation based on receptors overexpressed by tumor cells. ...
For example, NorthStar Medical Radioisotopes, in Beloit, Wisconsin, is currently producing molybdenum-99 using two different processes, one that involves no uranium and one that involves using particle accelerators. And Niowave, in Michigan, is also exploring methods of producing nonreactor, low-enriched–uranium methods of producing medical radioisotopes, ...
ZAP Surgical Systems, Inc. today announced it has received CE mark clearance to the new EU MDR for its ZAP-X® Gyroscopic Radiosurgery® platform. The CE mark makes it possible for healthcare providers to begin treating patients with the ZAP-X system in the European Union. For select indications including many primary and metastatic brain tumors, stereotactic radiosurgery (SRS) is proven ...
ZAP Surgical Systems, Inc. today announced it has received Shonin approval from the Japanese Pharmaceuticals and Medical Devices Agency (PMDA) for its ZAP-X® Gyroscopic Radiosurgery® platform. As part of the approval, ZAP-X is now cleared for clinical use in Japan. To facilitate a robust market introduction effort, ZAP also announced a partnership with MC Medical Inc. to lead Japanese ...
ZAP Surgical Systems, Inc. today announced ZAP-X® Gyroscopic Radiosurgery® patient treatments have commenced at MedStar Georgetown Cancer Institute at MedStar Southern Maryland Hospital Center in Clinton, MD. For many primary and metastatic brain tumors, stereotactic radiosurgery (SRS) has proven to be an effective treatment with outcomes equivalent to invasive surgical procedures. ...
Good News for Cancer and Heart Disease Patients: US Nuclear Partner Achieves Critical Milestone Proving New Way to Fill Multi-Billion/Year Shortage of Radioisotopes for Diagnostics and Treatments The National Academies of Sciences, Engineering and Medicine warns about severe shortages of radioisotopes that are required to non-invasively diagnose heart disease, ...
The lack of long-term radioactive waste is due to the fact that the Z-Pinch fusion reactor is fueled by an isotope of hydrogen from seawater rather than the highly enriched uranium that fuels the current fission reactor methods used to produce radioisotope products The Current Situation Radioisotopes are an essential part of both cancer treatment and medical ...
DENVER, CO / ACCESSWIRE / July 16, 2018 / On June 22nd a mechanical failure at the Lucas Heights nuclear reactor in Sydney, Australia shined a light on the tenuous supply chain of medical radioisotopes worldwide. These isotopes are key tools in both diagnosis and treatment for a wide range of medical conditions. ...
“The plan is to build these radioisotope generators and sell them for maybe $6-$10 million each. If you want to put up a nuclear reactor, you’re talking hundreds of millions of dollars to make the initial ...
In this context, the knowledge of the workforce composition in the facility responsible for the radioisotope production and its distribution was used. The individual monitoring programme has been carried out by individual dosimeters, TLDs, and internal contamination monitoring (in vivo method). The reported doses, in the period studied, suggest that the external exposure was the ...
Relevant procedure features, such as treatment room and facility, spatial distribution, source and target phantom as well as radioisotope type, can be easily introduced to the calculation code; this emphasises the versatility and potential of the computational tool. ...
Radiation Synovectomy (radiosynovectomy, radiosynoviorthesis or RSV) is a method of treatment by intra-articular application of beta-emitting radioisotopes. There are several radionuclides available for this treatment and some radiopharmaceuticals have been shown to be effective and safe for this procedure. ...
Anthropomorphic-anthropometrical phantoms are simulator objects for measuring absorbed dose in conditions equivalent to those found in the exposure of the internal organs to charged particles, photons or neutrons generated by external beams or to internal intake of radioisotopes. This paper addresses the construction of an anatomical simulator that retains the anthropomorphic and ...
The application of such methods to the radiopharmaceutical centre of IPEN is described.Keywords: knowledge mapping, knowledge assessment, knowledge-based strategy, critical knowledge, nuclear knowledge management, resource-based view, knowledge-based view, radioisotopes, radiopharmaceuticals, strategic ...