Clinical Tools Articles
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Lipids Used in COVID-19 mRNA Vaccines
The COVID-19 pandemic has killed millions of people. Vaccines certainly are the most outstanding ways to prevent major diseases and death, though they haven't eliminated infections. At present, the most effective vaccine is the mRNA vaccine developed by Pfizer-BioNTech and Moderna. Before that, mRNA technology stopped in the lab phase. How to apply mRNA technology to more complex diseases in the ...
By BOC Sciences
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Hypoglycemic Functional Factors in Natural Products and Their Mechanisms of Action
Diabetes is a common clinical disease, and with the improvement of living standards, an increase in the number of obese people, and the intensification of aging populations, the incidence of diabetes is increasing year by year. Diabetes has various types and requires long-term treatment. Antidiabetic drugs are essential for people with the disease. These drugs can be classified into insulin ...
By BOC Sciences
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Enhancing Healthcare Security: The Role of Door Frame Metal Detectors in Hospitals and Clinics
Enhancing Healthcare Security: The Role of Door Frame Metal Detectors in Hospitals and Clinics The safety and security of patients, healthcare professionals, and visitors are paramount in hospitals and clinics. With the evolving landscape of security threats, the implementation of robust security measures is essential to ensure a secure environment conducive to healing and care. Door frame metal ...
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Drug-Loaded Liposomes: Tiny Spheres with Big Potential
Imagine tiny bubbles, smaller than a red blood cell, carrying powerful medicines directly to diseased cells. This isn't science fiction, it's the cutting edge of drug delivery with drug-loaded liposomes. What are liposomes? Liposomes are microscopic spheres made from phospholipids, the same fatty molecules that make up cell membranes. These phospholipids naturally arrange themselves in ...
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Hydrogen peroxide preoxidation as a strategy for enhanced antimicrobial photodynamic action against methicillin-resistant Staphylococcus aureus
Antibiotic resistance is one of the main challenges in public health in the 21st century. It is mostly due to prolonged and/or inadequate use of antibiotics. These, along with antibiotic resistant bacteria, get into municipal and hospital wastewaters, and may be spread into water sources by inefficient disinfection. Antimicrobial photodynamic treatment (aPDT) may be an alternative to tackle ...
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Clinical Research On-Demand: How the University of Washington’s Theberge Lab is Using Tasso to Study Unpredictable Events in Real Time - Case Study
Many important research questions cannot be studied under controlled circumstances. Events like natural disasters or disease exposure often occur without warning and prevent in-person clinic visits, making timely observation difficult without a flexible approach. At the University of Washington, researchers are partnering with Tasso to study these scenarios by deploying on-demand remote ...
By Tasso, Inc.
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Bispecific Antibodies and Bispecific Antibody ADCs
With the rapid development of antibody-drug conjugate (ADC), more and more companies have entered the field of ADC research and development, and various types of ADC technologies and branches have emerged. Bispecific antibody conjugates (BsAb ADCs) are one of the emerging new technologies. The high specificity of bispecific antibodies enables more precise targeting of tumor cells. On the other ...
By BOC Sciences
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Mechanisms to Combat Drug Resistance: Overview of Antimicrobial Peptides
What are Antimicrobial Peptides? Antimicrobial peptides (AMPs) are naturally occurring peptide molecules found in various organisms, including humans, animals, plants, and microorganisms. These peptides play a crucial role in the innate immune system's defense against microbial infections, exhibiting antimicrobial properties that can inhibit the growth or kill bacteria, fungi, viruses, and even ...
By BOC Sciences
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Nano-Flow Cytometry: A Revolutionary Tool for Biomedical Research
Nano-flow cytometry is a revolutionary technology that has the potential to transform early disease detection and diagnosis. Nano-flow cytometers are able to detect and analyze individual nanoparticles, including extracellular vesicles and viruses, with high sensitivity and accuracy. This makes them ideal for detecting diseases at their earliest stages, when they are most treatable. How does ...
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API - Oseltamivir Phosphate
Introduction Oseltamivir phosphate is a white or almost white crystalline powder with the chemical name ethyl(3R,4R,5S)-4-acetamido-5-amino-3-(1-ethylpropoxy)-cyclohex-1-ene-1-carboxylate phosphate. It is an influenza viral neuraminidase inhibitor used in the prevention and treatment of influenza. Application in the treatment of influenza Introduction of influenza Influenza, also called flu or ...
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How to Conduct a Sustainability Gap Analysis for Healthcare Packaging
How To Conduct a Sustainability Gap Analysis for Healthcare Packaging Sustainability in modern healthcare is fundamental for mitigating environmental impact and contributing to the health of the planet. Sustainability in the healthcare packaging industry, for instance, is crucial to effectively reduce waste, conserve valuable resources, and promote sustainable practices. To achieve these ...
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Development of Gene Therapy Viral Vectors for Rare Diseases
In many cases, gene therapy requires a vector to deliver the gene therapy drug to the target cell. Viral vectors have been one of the most widely studied vectors due to their outstanding transduction efficiency and other significant advantages. Viral vector-based gene therapy has now achieved good clinical results. More than a dozen viral gene therapy products have been approved for the treatment ...
By Protheragen
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How to activate the "first responders" of the immune system - NK cells
About NK Cells Natural Killer (NK) cells play a critical role in the innate immune surveillance against cancer and viral infections. They are the "first responders" capable of spontaneously recognizing abnormal cells in the body, swiftly eliminating them through targeted cytotoxic mechanisms, and effectively producing pro-inflammatory cytokines and chemokines to recruit and activate other immune ...
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ADC Drugs For HER2 Positive Breast Cancer
According to the latest data, breast cancer has overtaken lung cancer to become the most common cancer among women, and the death rate is the second highest among female tumors, seriously affecting the physical and mental health of women around the world. Patients with abnormal expression of human epidermal growth factor receptor (HER2) account for 15%-20% of all breast cancers, which is highly ...
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Worried About ChatGPT? Why Large Language Models Increase Healthcare Risks
Large language models (LLMs) are a type of artificial intelligence (AI) that can be used to generate text, translate languages, produce different kinds of content, and answer people’s questions. LLMs have great potential to transform many industries, healthcare included. “Potential healthcare applications of LLMs span patient care, research and workflow optimization (clinical and ...
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Monoaromatic Heterocyclic Chemistry: Applications and Synthesis
Summary Heterocyclic compounds with aromatic characteristics are called aromatic heterocyclic compounds, which can be classified into monoaromatic heterocycles and fused heterocycles. The common monoaromatic heterocycles are five-membered Furan, Pyrrole, Thiophene, Pyrazole, Imidazole, Oxazole, etc., and six-membered Pyridine, Pyranone, Pyridazine, Pyrimidine, Triazine, etc. Aromatic ...
By BOC Sciences
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Development Trends And Potential Challenges of PROTACs
PROTAC technology has been in development for more than 20 years. PROTAC proof-of-concept studies date back to 2001, when Crews' team tested the possibility of artificially induced intracellular protein degradation with a peptide that was too large in molecular weight and required cells to penetrate the peptide to improve cell permeability. The discovery of the first small molecule PROTAC and the ...
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Evolutionary, Medical, and Clinical Applications of Whole Exome Sequencing
As we all know, proteins play important roles in human bodies since all physiologic events are related to the structural or mechanical functions of certain proteins. Studying the synthesis process of proteins is a way to study the etiology, pathophysiology, diagnosis, and treatment of certain diseases. The human genome contains approximately 3 billion base pairs of DNA. Among them, only about 30 ...
By CD Genomics
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A Natural Polysaccharide-based Bioadhesive for Wound Repair Found
Hundreds of millions of people suffer skin tissue damage every year, including accidental injury, surgical injury, chronic ulcer, etc., and severe cases may lead to amputation or even life-threatening. Suturing is currently the preferred method for clinically closing wounds. However, wound suturing takes a long time during the operation, and removing the stitches will cause secondary damage to ...
By CD BioGlyco.
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What is the ICD code for HFpEF?
Heart failure with preserved ejection fraction (HFpEF) is currently affecting over half of heart failure patients. The Centers for Medicare and Medicaid Services (CMS) and the National Center for Health Statistics (NCHS), two departments within the U.S. Federal Government’s Department of Health and Human Services (DHHS), use the International Classification of Diseases (ICD) for coding ...
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