Mikrogen GmbH products

Recombinant Hepatitis C virus Core protein is expressed in E. coli as a monomeric, non-glycosylated polypeptide chain consisting of 115 amino acids with a molecular mass of 13100 Da. The product represents amino acids 1 to 115 of the HCV polyprotein, covering the N-terminal region (“domain I”) of the mature Core protein. It lacks the C-terminal signal peptide, the transmembrane region and the ER anchoring sequence (“domain II”) of the native protein.

Recombinant Hepatitis C virus NS3 is expressed in E. coli as a monomeric, non-glycosylated polypeptide chain consisting of 538 amino acids with a molecular mass of 56600 Da. The product represents amino acids 1007 to 1534 of the HCV polyprotein, covering the serine protease domain as well as the major part of the helicase domain.